Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005576 | cellular_component | extracellular region |
A | 0005886 | cellular_component | plasma membrane |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0042597 | cellular_component | periplasmic space |
A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue 9F2 A 301 |
Chain | Residue |
A | SER70 |
A | GLY240 |
A | ASP241 |
A | HOH447 |
A | HOH470 |
A | HOH500 |
A | HOH517 |
A | ILE103 |
A | SER128 |
A | PRO169 |
A | ASN172 |
A | LYS236 |
A | THR237 |
A | GLY238 |
A | THR239 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FaFCSTfKaplVAAVL |
Chain | Residue | Details |
A | PHE66-LEU81 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER70 | |
Chain | Residue | Details |
A | GLU168 | |
Chain | Residue | Details |
A | SER128 | |
A | THR237 | |
Chain | Residue | Details |
A | LYS73 | |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | SITE: Functions as a gatekeeper residue that regulates substrate accessibility to the enzyme active site => ECO:0000303|PubMed:24023821 |
Chain | Residue | Details |
A | ILE103 | |