6B65
IMPase (AF2372) R92Q/K164E
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006020 | biological_process | inositol metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| A | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| A | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
| B | 0006020 | biological_process | inositol metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| B | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| B | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 901 |
| Chain | Residue |
| A | GLU67 |
| B | IPA301 |
| A | ASP82 |
| A | LEU84 |
| A | ASP85 |
| A | GLY86 |
| A | THR87 |
| A | ARG197 |
| A | MG903 |
| A | HOH1009 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 902 |
| Chain | Residue |
| A | ASP38 |
| A | THR40 |
| A | PRO41 |
| A | GLU67 |
| A | GLU68 |
| A | MG903 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 903 |
| Chain | Residue |
| A | ASP46 |
| A | GLU67 |
| A | GLU68 |
| A | SO4901 |
| A | MG902 |
| A | HOH1009 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 904 |
| Chain | Residue |
| A | THR122 |
| A | ASP124 |
| A | HOH1013 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue IPA B 301 |
| Chain | Residue |
| A | THR87 |
| A | PHE88 |
| A | SO4901 |
| B | ARG165 |
| B | ARG167 |
| B | HOH419 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | GLU67 |
| B | ASP82 |
| B | LEU84 |
| B | ASP85 |
| B | GLY86 |
| B | THR87 |
| B | ARG197 |
| B | MG304 |
| B | IPA307 |
| B | HOH401 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | ASP38 |
| B | THR40 |
| B | PRO41 |
| B | GLU67 |
| B | GLU68 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 304 |
| Chain | Residue |
| B | ASP46 |
| B | GLU67 |
| B | GLU68 |
| B | SO4302 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 305 |
| Chain | Residue |
| B | THR122 |
| B | ASP124 |
| B | ARG135 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 306 |
| Chain | Residue |
| B | ARG11 |
| B | GLU125 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue IPA B 307 |
| Chain | Residue |
| A | ARG165 |
| A | ARG167 |
| B | THR87 |
| B | PHE88 |
| B | SO4302 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP200 | |
| B | ASP38 | |
| B | THR40 | |
| B | GLU67 | |
| B | ASP82 | |
| B | LEU84 | |
| B | ASP85 | |
| B | ARG167 | |
| B | ALA172 | |
| B | ARG191 | |
| A | THR40 | |
| B | ASP200 | |
| A | GLU67 | |
| A | ASP82 | |
| A | LEU84 | |
| A | ASP85 | |
| A | ARG167 | |
| A | ALA172 | |
| A | ARG191 |
