Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0016999 | biological_process | antibiotic metabolic process |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0016999 | biological_process | antibiotic metabolic process |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | LEU110 |
| A | ARG311 |
| A | ALA361 |
| A | PHE362 |
| A | GLY363 |
| A | HIS367 |
| A | CYS369 |
| A | GLY371 |
| A | ALA375 |
| A | CGM502 |
| A | EDO512 |
| A | LEU111 |
| A | HOH643 |
| A | HOH647 |
| A | HIS118 |
| A | ARG122 |
| A | PHE129 |
| A | ILE174 |
| A | GLY260 |
| A | THR263 |
| A | THR264 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue CGM A 502 |
| Chain | Residue |
| A | GLY102 |
| A | GLU103 |
| A | GLU105 |
| A | LEU111 |
| A | ALA195 |
| A | ARG197 |
| A | PRO198 |
| A | ALA204 |
| A | LEU255 |
| A | ALA306 |
| A | HEM501 |
| A | EDO512 |
| A | EDO513 |
| A | HOH634 |
| A | HOH643 |
| A | HOH666 |
| A | HOH689 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | PHE43 |
| A | GLN277 |
| A | HIS278 |
| A | TYR302 |
| A | EDO516 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ASP76 |
| A | ARG79 |
| B | TYR414 |
| B | GLU415 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ARG86 |
| A | GLU318 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | PRO36 |
| A | PRO198 |
| A | SER408 |
| A | HOH655 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | ARG394 |
| B | TRP282 |
| B | PRO391 |
| B | ALA392 |
| B | LEU393 |
| B | HOH604 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | THR396 |
| B | ARG283 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | GLU341 |
| A | ALA342 |
| A | SER345 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | THR153 |
| A | ALA154 |
| A | EDO511 |
| A | HOH603 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | ASP157 |
| A | EDO510 |
| A | HOH603 |
| A | HOH678 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | ARG310 |
| A | HEM501 |
| A | CGM502 |
| A | EDO513 |
| A | HOH643 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | GLY308 |
| A | LEU309 |
| A | ARG310 |
| A | CGM502 |
| A | EDO512 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | ASP398 |
| A | ALA400 |
| A | HOH650 |
| B | HIS278 |
| B | ALA349 |
| B | PHE350 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | GLU298 |
| A | ALA356 |
| A | ARG357 |
| A | HIS359 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 516 |
| Chain | Residue |
| A | HIS278 |
| A | ALA349 |
| A | PHE350 |
| A | EDO503 |
| site_id | AD8 |
| Number of Residues | 21 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | ARG122 |
| B | PHE129 |
| B | LEU255 |
| B | GLY260 |
| B | THR263 |
| B | THR264 |
| B | MET267 |
| B | ALA306 |
| B | LEU309 |
| B | ARG311 |
| B | ALA361 |
| B | PHE362 |
| B | GLY363 |
| B | HIS367 |
| B | CYS369 |
| B | ALA375 |
| B | CGM502 |
| B | EDO504 |
| B | LEU110 |
| B | LEU111 |
| B | HIS118 |
| site_id | AD9 |
| Number of Residues | 18 |
| Details | binding site for residue CGM B 502 |
| Chain | Residue |
| B | SER100 |
| B | GLY102 |
| B | GLU103 |
| B | GLU105 |
| B | LEU111 |
| B | ALA195 |
| B | ARG197 |
| B | PRO198 |
| B | ALA204 |
| B | LEU205 |
| B | VAL254 |
| B | LEU255 |
| B | ALA306 |
| B | ALA409 |
| B | HEM501 |
| B | EDO504 |
| B | HOH640 |
| B | HOH653 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| A | ASP398 |
| B | HIS278 |
| B | THR280 |
| B | ALA281 |
| B | PHE350 |
| B | ASP351 |
| B | ILE352 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | ARG310 |
| B | ARG311 |
| B | HEM501 |
| B | CGM502 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| A | GLU56 |
| B | ASP150 |
| B | ASP151 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | GLU262 |
| B | SER266 |
| B | LYS405 |
| B | VAL413 |
| B | HOH629 |
| B | HOH632 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGyGPHQCLG |
| Chain | Residue | Details |
| A | PHE362-GLY371 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P18326","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P18326","evidenceCode":"ECO:0000250"}]} |
