6B0Q

Zinc finger Domain of WT1(-KTS form) with 13+1mer Oligonucleotide with 3' Triplet TGT

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN D 501

Chain	Residue
D	CYS325
D	CYS330
D	HIS343
D	HIS347

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN D 502

Chain	Residue
D	CYS355
D	CYS360
D	HIS373
D	HIS377

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN D 503

Chain	Residue
D	CYS388
D	HIS401
D	HIS405
D	CYS385

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 504

Chain	Residue
D	CYS413
D	CYS418
D	HIS431
D	HIS435

---

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 D 505

Chain	Residue
A	ARG321
A	LYS332
A	ARG333
D	ARG362

---

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 D 506

Chain	Residue
D	TYR334
D	PHE335
D	LYS336
D	HIS339

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 D 507

Chain	Residue
A	ARG437
D	LYS336
D	LEU337
D	SER338

---

site_id	AC8
Number of Residues	1
Details	binding site for residue SO4 D 508

Chain	Residue
D	ARG390

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	CYS325
A	CYS330
A	HIS343
A	HIS347

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN A 502

Chain	Residue
A	CYS355
A	CYS360
A	HIS373
A	HIS377

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN A 503

Chain	Residue
A	CYS385
A	CYS388
A	HIS401
A	HIS405

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN A 504

Chain	Residue
A	CYS413
A	CYS418
A	HIS431
A	HIS435

---

site_id	AD4
Number of Residues	2
Details	binding site for residue SO4 A 505

Chain	Residue
A	ARG362
A	ARG376

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 A 506

Chain	Residue
A	TYR334
A	PHE335
A	LYS336
A	HIS339

---

site_id	AD6
Number of Residues	6
Details	binding site for residue SO4 A 507

Chain	Residue
A	LYS332
A	TYR334
A	HIS343
A	LYS346
D	GLU350
D	LYS351

---

site_id	AD7
Number of Residues	1
Details	binding site for residue SO4 A 508

Chain	Residue
A	ARG390

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CaypgCnkrYfklshlqmHsrk..H

Chain	Residue	Details
D	CYS325-HIS347
D	CYS355-HIS377
D	CYS385-HIS405
D	CYS413-HIS435

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Zinc finger: {"description":"C2H2-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	48
Details	Zinc finger: {"description":"C2H2-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	44
Details	Zinc finger: {"description":"C2H2-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	48
Details	Zinc finger: {"description":"C2H2-type 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	44
Details	Region: {"description":"Important for interaction with target DNA"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Site: {"description":"Important for interaction with target DNA"}

Chain

Residue

Details

---