6AL3

Lys49 PLA2 BPII derived from the venom of Protobothrops flavoviridis.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004623	molecular_function	A2-type glycerophospholipase activity
A	0005509	molecular_function	calcium ion binding
A	0005543	molecular_function	phospholipid binding
A	0005576	cellular_component	extracellular region
A	0006644	biological_process	phospholipid metabolic process
A	0016042	biological_process	lipid catabolic process
A	0042130	biological_process	negative regulation of T cell proliferation
A	0050482	biological_process	arachidonate secretion
B	0004623	molecular_function	A2-type glycerophospholipase activity
B	0005509	molecular_function	calcium ion binding
B	0005543	molecular_function	phospholipid binding
B	0005576	cellular_component	extracellular region
B	0006644	biological_process	phospholipid metabolic process
B	0016042	biological_process	lipid catabolic process
B	0042130	biological_process	negative regulation of T cell proliferation
B	0050482	biological_process	arachidonate secretion
C	0004623	molecular_function	A2-type glycerophospholipase activity
C	0005509	molecular_function	calcium ion binding
C	0005543	molecular_function	phospholipid binding
C	0005576	cellular_component	extracellular region
C	0006644	biological_process	phospholipid metabolic process
C	0016042	biological_process	lipid catabolic process
C	0042130	biological_process	negative regulation of T cell proliferation
C	0050482	biological_process	arachidonate secretion
D	0004623	molecular_function	A2-type glycerophospholipase activity
D	0005509	molecular_function	calcium ion binding
D	0005543	molecular_function	phospholipid binding
D	0005576	cellular_component	extracellular region
D	0006644	biological_process	phospholipid metabolic process
D	0016042	biological_process	lipid catabolic process
D	0042130	biological_process	negative regulation of T cell proliferation
D	0050482	biological_process	arachidonate secretion

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG32
B	ARG33
B	LYS52

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site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 B 202

Chain	Residue
B	LYS117
B	LYS118

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 C 201

Chain	Residue
A	PRO81
C	LYS15
C	LYS19
C	ASN20

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Functional Information from PROSITE/UniProt

site_id	PS00118
Number of Residues	8
Details	PA2_HIS Phospholipase A2 histidine active site. CCYvHKcC

Chain	Residue	Details
A	CYS43-CYS50

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site_id	PS00119
Number of Residues	11
Details	PA2_ASP Phospholipase A2 aspartic acid active site. VCECDKAVaIC

Chain	Residue	Details
A	VAL86-CYS96

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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