Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6AIT

Crystal structure of E. coli BepA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003756	molecular_function	protein disulfide isomerase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0005515	molecular_function	protein binding
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
A	0046872	molecular_function	metal ion binding
A	0051603	biological_process	proteolysis involved in protein catabolic process
A	0061077	biological_process	chaperone-mediated protein folding
B	0003756	molecular_function	protein disulfide isomerase activity
B	0004222	molecular_function	metalloendopeptidase activity
B	0005515	molecular_function	protein binding
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042597	cellular_component	periplasmic space
B	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
B	0046872	molecular_function	metal ion binding
B	0051603	biological_process	proteolysis involved in protein catabolic process
B	0061077	biological_process	chaperone-mediated protein folding
C	0003756	molecular_function	protein disulfide isomerase activity
C	0004222	molecular_function	metalloendopeptidase activity
C	0005515	molecular_function	protein binding
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0008270	molecular_function	zinc ion binding
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0042597	cellular_component	periplasmic space
C	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
C	0046872	molecular_function	metal ion binding
C	0051603	biological_process	proteolysis involved in protein catabolic process
C	0061077	biological_process	chaperone-mediated protein folding
D	0003756	molecular_function	protein disulfide isomerase activity
D	0004222	molecular_function	metalloendopeptidase activity
D	0005515	molecular_function	protein binding
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0008270	molecular_function	zinc ion binding
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0042597	cellular_component	periplasmic space
D	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
D	0046872	molecular_function	metal ion binding
D	0051603	biological_process	proteolysis involved in protein catabolic process
D	0061077	biological_process	chaperone-mediated protein folding
E	0003756	molecular_function	protein disulfide isomerase activity
E	0004222	molecular_function	metalloendopeptidase activity
E	0005515	molecular_function	protein binding
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0008237	molecular_function	metallopeptidase activity
E	0008270	molecular_function	zinc ion binding
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0042597	cellular_component	periplasmic space
E	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
E	0046872	molecular_function	metal ion binding
E	0051603	biological_process	proteolysis involved in protein catabolic process
E	0061077	biological_process	chaperone-mediated protein folding
F	0003756	molecular_function	protein disulfide isomerase activity
F	0004222	molecular_function	metalloendopeptidase activity
F	0005515	molecular_function	protein binding
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0008237	molecular_function	metallopeptidase activity
F	0008270	molecular_function	zinc ion binding
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0030288	cellular_component	outer membrane-bounded periplasmic space
F	0042597	cellular_component	periplasmic space
F	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
F	0046872	molecular_function	metal ion binding
F	0051603	biological_process	proteolysis involved in protein catabolic process
F	0061077	biological_process	chaperone-mediated protein folding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	HIS136
A	HIS140
A	GLU201
A	HIS246

site_id	AC2
Number of Residues	6
Details	binding site for residue TRS A 502

Chain	Residue
A	HOH625
A	ASP69
A	PRO70
A	ASP347
A	ASP351
A	ASN381

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 501

Chain	Residue
B	HIS136
B	HIS140
B	GLU201
B	HIS246

site_id	AC4
Number of Residues	6
Details	binding site for residue TRS B 502

Chain	Residue
B	ASP69
B	PRO70
B	ASP347
B	ASP351
B	ASN381
B	ASN384

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 501

Chain	Residue
C	HIS136
C	HIS140
C	GLU201
C	HIS246

site_id	AC6
Number of Residues	3
Details	binding site for residue TRS C 502

Chain	Residue
C	ASP347
C	ASP351
C	ASN381

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 501

Chain	Residue
D	HIS136
D	HIS140
D	GLU201
D	HIS246

site_id	AC8
Number of Residues	5
Details	binding site for residue TRS D 502

Chain	Residue
D	ASP69
D	PRO70
D	ASP347
D	ASP351
D	ASN381

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN E 501

Chain	Residue
E	HIS136
E	HIS140
E	GLU201
E	HIS246

site_id	AD1
Number of Residues	4
Details	binding site for residue TRS E 502

Chain	Residue
E	PRO70
E	ASP347
E	ASP351
E	ASN381

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN F 501

Chain	Residue
F	HIS136
F	HIS140
F	GLU201
F	HIS246

site_id	AD3
Number of Residues	5
Details	binding site for residue TRS F 502

Chain	Residue
F	ASP347
F	ASP351
F	ASN381
F	HOH602
F	HOH605

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_00997

Chain	Residue	Details
A	GLU137
B	GLU137
C	GLU137
D	GLU137
E	GLU137
F	GLU137

site_id	SWS_FT_FI2
Number of Residues	6
Details	ACT_SITE: Proton donor => ECO:0000255\|HAMAP-Rule:MF_00997

Chain	Residue	Details
A	ASP205
B	ASP205
C	ASP205
D	ASP205
E	ASP205
F	ASP205

site_id	SWS_FT_FI3
Number of Residues	18
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00997

Chain	Residue	Details
A	HIS136
D	HIS136
D	HIS140
D	GLU201
E	HIS136
E	HIS140
E	GLU201
F	HIS136
F	HIS140
F	GLU201
A	HIS140
A	GLU201
B	HIS136
B	HIS140
B	GLU201
C	HIS136
C	HIS140
C	GLU201

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)