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6AGO

Crystal structure of MRG15-ASH1L Histone methyltransferase complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0042054molecular_functionhistone methyltransferase activity
B0005634cellular_componentnucleus
B0042054molecular_functionhistone methyltransferase activity
C0005634cellular_componentnucleus
C0006325biological_processchromatin organization
C0006355biological_processregulation of DNA-templated transcription
D0005634cellular_componentnucleus
D0006325biological_processchromatin organization
D0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue SAM A 2301
ChainResidue
AGLU2149
APHE2215
AILE2216
AASN2217
AHIS2218
ATYR2255
ALYS2269
ACYS2270
ALYS2150
AGLY2151
ATRP2152
ASER2191
AASP2192
AHIS2193
ATYR2194
AARG2214

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN A 2302
ChainResidue
ACYS2220
ACYS2268
ACYS2270
ACYS2275

site_idAC3
Number of Residues5
Detailsbinding site for residue ZN A 2303
ChainResidue
ACYS2091
ACYS2093
ACYS2104
ACYS2108
AZN2304

site_idAC4
Number of Residues6
Detailsbinding site for residue ZN A 2304
ChainResidue
ACYS2091
ACYS2104
ACYS2117
ACYS2122
ACYS2128
AZN2303

site_idAC5
Number of Residues4
Detailsbinding site for residue ZN B 2301
ChainResidue
BCYS2220
BCYS2268
BCYS2270
BCYS2275

site_idAC6
Number of Residues3
Detailsbinding site for residue ZN B 2302
ChainResidue
BCYS2091
BCYS2104
BCYS2108

site_idAC7
Number of Residues5
Detailsbinding site for residue ZN B 2303
ChainResidue
BCYS2091
BCYS2104
BCYS2117
BCYS2122
BCYS2128

226707

PDB entries from 2024-10-30

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