Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0042054 | molecular_function | histone methyltransferase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006325 | biological_process | chromatin organization |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0005634 | cellular_component | nucleus |
| D | 0006325 | biological_process | chromatin organization |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue SAM A 2301 |
| Chain | Residue |
| A | GLU2149 |
| A | PHE2215 |
| A | ILE2216 |
| A | ASN2217 |
| A | HIS2218 |
| A | TYR2255 |
| A | LYS2269 |
| A | CYS2270 |
| A | LYS2150 |
| A | GLY2151 |
| A | TRP2152 |
| A | SER2191 |
| A | ASP2192 |
| A | HIS2193 |
| A | TYR2194 |
| A | ARG2214 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2302 |
| Chain | Residue |
| A | CYS2220 |
| A | CYS2268 |
| A | CYS2270 |
| A | CYS2275 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 2303 |
| Chain | Residue |
| A | CYS2091 |
| A | CYS2093 |
| A | CYS2104 |
| A | CYS2108 |
| A | ZN2304 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 2304 |
| Chain | Residue |
| A | CYS2091 |
| A | CYS2104 |
| A | CYS2117 |
| A | CYS2122 |
| A | CYS2128 |
| A | ZN2303 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 2301 |
| Chain | Residue |
| B | CYS2220 |
| B | CYS2268 |
| B | CYS2270 |
| B | CYS2275 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ZN B 2302 |
| Chain | Residue |
| B | CYS2091 |
| B | CYS2104 |
| B | CYS2108 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 2303 |
| Chain | Residue |
| B | CYS2091 |
| B | CYS2104 |
| B | CYS2117 |
| B | CYS2122 |
| B | CYS2128 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 102 |
| Details | Domain: {"description":"AWS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00562","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 116 |
| Details | Domain: {"description":"SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 42 |
| Details | Region: {"description":"Interaction with RB1-2"} |
