6AEX

Crystal structure of unoccupied murine uPAR

Functional Information from GO Data

Chain	GOid	namespace	contents
U	0001934	biological_process	positive regulation of protein phosphorylation
U	0005102	molecular_function	signaling receptor binding
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005886	cellular_component	plasma membrane
U	0009897	cellular_component	external side of plasma membrane
U	0009986	cellular_component	cell surface
U	0010755	biological_process	regulation of plasminogen activation
U	0019899	molecular_function	enzyme binding
U	0019904	molecular_function	protein domain specific binding
U	0030155	biological_process	regulation of cell adhesion
U	0030377	molecular_function	urokinase plasminogen activator receptor activity
U	0031639	biological_process	plasminogen activation
U	0034112	biological_process	positive regulation of homotypic cell-cell adhesion
U	0034394	biological_process	protein localization to cell surface
U	0038195	biological_process	urokinase plasminogen activator signaling pathway
U	0043066	biological_process	negative regulation of apoptotic process
U	0045742	biological_process	positive regulation of epidermal growth factor receptor signaling pathway
U	0048762	biological_process	mesenchymal cell differentiation
U	0051917	biological_process	regulation of fibrinolysis
U	0060742	biological_process	epithelial cell differentiation involved in prostate gland development
U	0090200	biological_process	positive regulation of release of cytochrome c from mitochondria
U	0098552	cellular_component	side of membrane
U	0098637	cellular_component	protein complex involved in cell-matrix adhesion
U	1905370	cellular_component	serine-type endopeptidase complex
U	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00983
Number of Residues	44
Details	LY6_UPAR Ly-6 / u-PAR domain signature. QCMqCesnqs...Clve.....ECAlgqdlCrttvlrewqddrelevvtrg....C

Chain	Residue	Details
U	GLN2-CYS45
U	GLU95-CYS145
U	GLN191-CYS245

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20133942","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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