Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6ACE

histone lysine desuccinylase Sirt5 in complex with succinyl peptide H3K122

Functional Information from GO Data
ChainGOidnamespacecontents
A0036054molecular_functionprotein-malonyllysine demalonylase activity
A0036055molecular_functionprotein-succinyllysine desuccinylase activity
A0070403molecular_functionNAD+ binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 401
ChainResidue
ACYS166
ACYS169
ACYS207
ACYS212

site_idAC2
Number of Residues8
Detailsbinding site for residue GOL A 402
ChainResidue
AILE142
AASP143
AHOH516
AALA59
AVAL67
ATHR69
AARG105
AASN141

site_idAC3
Number of Residues5
Detailsbinding site for residue GOL A 403
ChainResidue
AGLU144
ATYR176
ASER185
ALYS187
AHOH505

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:27436229
ChainResidueDetails
BSLL122

site_idSWS_FT_FI2
Number of Residues5
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160, ECO:0000269|PubMed:22076378, ECO:0000269|PubMed:22767592, ECO:0000269|Ref.19
ChainResidueDetails
AGLY58
AGLN140
AGLY249
AASN275
ACYS293

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160
ChainResidueDetails
ATYR102
AARG105
ACYS166
ACYS169
ACYS207
ACYS212

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon