6ACE
histone lysine desuccinylase Sirt5 in complex with succinyl peptide H3K122
Functional Information from GO Data
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 401 |
Chain | Residue |
A | CYS166 |
A | CYS169 |
A | CYS207 |
A | CYS212 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue GOL A 402 |
Chain | Residue |
A | ILE142 |
A | ASP143 |
A | HOH516 |
A | ALA59 |
A | VAL67 |
A | THR69 |
A | ARG105 |
A | ASN141 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue GOL A 403 |
Chain | Residue |
A | GLU144 |
A | TYR176 |
A | SER185 |
A | LYS187 |
A | HOH505 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:27436229 |
Chain | Residue | Details |
B | SLL122 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160, ECO:0000269|PubMed:22076378, ECO:0000269|PubMed:22767592, ECO:0000269|Ref.19 |
Chain | Residue | Details |
A | GLY58 | |
A | GLN140 | |
A | GLY249 | |
A | ASN275 | |
A | CYS293 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160 |
Chain | Residue | Details |
A | TYR102 | |
A | ARG105 | |
A | CYS166 | |
A | CYS169 | |
A | CYS207 | |
A | CYS212 |