Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008720 | molecular_function | D-lactate dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008720 | molecular_function | D-lactate dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | VAL35 |
| A | ARG36 |
| A | HOH503 |
| A | HOH545 |
| B | LYS34 |
| B | VAL35 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HOH507 |
| B | LYS95 |
| A | PRO209 |
| A | LEU210 |
| A | ARG237 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | THR313 |
| A | ASN316 |
| A | HOH561 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | HIS105 |
| A | LYS156 |
| B | TYR145 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | ASN119 |
| A | LYS121 |
| A | GLY229 |
| A | GLY256 |
| A | HOH532 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | TYR145 |
| B | HIS105 |
| B | LYS156 |
| B | GOL409 |
| B | HOH511 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | CYS79 |
| B | ALA80 |
| B | ARG98 |
| B | PRO100 |
| B | ALA101 |
| B | ARG237 |
| B | GOL408 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| A | LYS95 |
| B | PRO209 |
| B | LEU210 |
| B | ARG237 |
| B | GOL410 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | THR313 |
| B | ASN316 |
| B | HOH521 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| A | ASP143 |
| B | PRO104 |
| B | HIS105 |
| B | ALA106 |
| B | GLU305 |
| B | ALA306 |
| B | HOH501 |
| B | HOH511 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 406 |
| Chain | Residue |
| A | PHE321 |
| B | GLY155 |
| B | ASP176 |
| B | LEU177 |
| B | PHE178 |
| B | GOL410 |
| B | HOH502 |
| B | HOH508 |
| B | HOH557 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 407 |
| Chain | Residue |
| B | ASN119 |
| B | LYS121 |
| B | GLY229 |
| B | GLY256 |
| B | HOH541 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 408 |
| Chain | Residue |
| B | ILE107 |
| B | THR235 |
| B | GLY236 |
| B | ARG237 |
| B | HIS298 |
| B | SO4402 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 409 |
| Chain | Residue |
| A | ARG325 |
| B | TYR102 |
| B | LYS156 |
| B | SO4401 |
| B | HOH511 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 410 |
| Chain | Residue |
| A | ASP320 |
| A | PHE321 |
| A | GLY324 |
| A | ARG325 |
| A | LEU327 |
| B | PRO209 |
| B | SO4403 |
| B | GOL406 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 411 |
| Chain | Residue |
| B | VAL99 |
| B | PRO100 |
| B | TYR102 |
| B | ALA309 |
| B | ILE310 |
| B | THR313 |
Functional Information from PROSITE/UniProt
| site_id | PS00065 |
| Number of Residues | 28 |
| Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. AGIIGtGKIGqilikilrgfdmk.VIaYD |
| Chain | Residue | Details |
| A | ALA149-ASP176 |
| site_id | PS00670 |
| Number of Residues | 23 |
| Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LYanSDIIsLNcPltkdTkyMiN |
| Chain | Residue | Details |
| A | LEU197-ASN219 |
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKdGvILVNtGRGmLID |
| Chain | Residue | Details |
| A | MET226-ASP242 |
