6AAO

Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 501

Chain	Residue
A	ATP504
A	HOH647
A	HOH710
A	HOH740
A	HOH762

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site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 502

Chain	Residue
A	HOH634
A	HOH751
A	GLU396
A	SER399
A	MG503
A	ATP504

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 503

Chain	Residue
A	GLU207
A	GLU396
A	MG502
A	ATP504
A	HOH634
A	HOH748

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site_id	AC4
Number of Residues	27
Details	binding site for residue ATP A 504

Chain	Residue
A	GLU207
A	ARG330
A	GLU332
A	HIS338
A	LEU339
A	PHE342
A	MET344
A	GLU396
A	LEU397
A	SER398
A	SER399
A	GLY421
A	GLY423
A	ARG426
A	MG501
A	MG502
A	MG503
A	9U0505
A	HOH615
A	HOH634
A	HOH647
A	HOH710
A	HOH740
A	HOH751
A	HOH755
A	HOH762
A	HOH772

---

site_id	AC5
Number of Residues	17
Details	binding site for residue 9U0 A 505

Chain	Residue
A	ALA302
A	LEU305
A	ALA306
A	MET344
A	ASN346
A	CYS348
A	PHE384
A	SER399
A	ASP408
A	ILE413
A	TRP417
A	GLY419
A	ALA420
A	GLY421
A	ATP504
A	HOH637
A	HOH745

---

site_id	AC6
Number of Residues	6
Details	binding site for residue K A 506

Chain	Residue
A	ASN203
A	PRO204
A	ASP206
A	HOH606
A	HOH608
A	HOH842

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site_id	AC7
Number of Residues	2
Details	binding site for residue K A 507

Chain	Residue
A	GLU341
A	ARG442

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site_id	AC8
Number of Residues	8
Details	binding site for residue PEG A 508

Chain	Residue
A	SER333
A	ASP334
A	GLY335
A	LYS336
A	GLU337
A	HIS338
A	HOH768
A	HOH889

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