6A7V
Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0044003 | biological_process | symbiont-mediated perturbation of host process |
| A | 0075136 | biological_process | response to host |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004540 | molecular_function | RNA nuclease activity |
| C | 0017148 | biological_process | negative regulation of translation |
| C | 0044003 | biological_process | symbiont-mediated perturbation of host process |
| C | 0075136 | biological_process | response to host |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004540 | molecular_function | RNA nuclease activity |
| E | 0017148 | biological_process | negative regulation of translation |
| E | 0044003 | biological_process | symbiont-mediated perturbation of host process |
| E | 0075136 | biological_process | response to host |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0004540 | molecular_function | RNA nuclease activity |
| G | 0017148 | biological_process | negative regulation of translation |
| G | 0044003 | biological_process | symbiont-mediated perturbation of host process |
| G | 0075136 | biological_process | response to host |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 1PE A 201 |
| Chain | Residue |
| A | GLU39 |
| G | ALA73 |
| G | ARG77 |
| A | ASN63 |
| A | HOH311 |
| A | HOH350 |
| A | HOH359 |
| A | HOH383 |
| C | ALA73 |
| C | ARG77 |
| E | ASN63 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | GLY48 |
| C | ALA49 |
| C | LEU50 |
| C | ASP51 |
| C | THR54 |
| C | HOH302 |
| D | GLY53 |
| D | TRP54 |
| D | GLU55 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 U 101 |
| Chain | Residue |
| C | ALA0 |
| C | ARG34 |
| C | ARG111 |
| U | THR24 |
| U | ARG26 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 496 |
| Details | Domain: {"description":"PINc","evidences":[{"source":"HAMAP-Rule","id":"MF_00265","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00265","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
