6A7V

Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004518	molecular_function	nuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0005515	molecular_function	protein binding
A	0017148	biological_process	negative regulation of translation
A	0044003	biological_process	symbiont-mediated perturbation of host process
A	0046872	molecular_function	metal ion binding
A	0075136	biological_process	response to host
C	0000287	molecular_function	magnesium ion binding
C	0004518	molecular_function	nuclease activity
C	0004540	molecular_function	RNA nuclease activity
C	0005515	molecular_function	protein binding
C	0017148	biological_process	negative regulation of translation
C	0044003	biological_process	symbiont-mediated perturbation of host process
C	0046872	molecular_function	metal ion binding
C	0075136	biological_process	response to host
E	0000287	molecular_function	magnesium ion binding
E	0004518	molecular_function	nuclease activity
E	0004540	molecular_function	RNA nuclease activity
E	0005515	molecular_function	protein binding
E	0017148	biological_process	negative regulation of translation
E	0044003	biological_process	symbiont-mediated perturbation of host process
E	0046872	molecular_function	metal ion binding
E	0075136	biological_process	response to host
G	0000287	molecular_function	magnesium ion binding
G	0004518	molecular_function	nuclease activity
G	0004540	molecular_function	RNA nuclease activity
G	0005515	molecular_function	protein binding
G	0017148	biological_process	negative regulation of translation
G	0044003	biological_process	symbiont-mediated perturbation of host process
G	0046872	molecular_function	metal ion binding
G	0075136	biological_process	response to host

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue 1PE A 201

Chain	Residue
A	GLU39
G	ALA73
G	ARG77
A	ASN63
A	HOH311
A	HOH350
A	HOH359
A	HOH383
C	ALA73
C	ARG77
E	ASN63

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site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 C 201

Chain	Residue
C	GLY48
C	ALA49
C	LEU50
C	ASP51
C	THR54
C	HOH302
D	GLY53
D	TRP54
D	GLU55

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site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 U 101

Chain	Residue
C	ALA0
C	ARG34
C	ARG111
U	THR24
U	ARG26

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00265

Chain	Residue	Details
A	ASP5
A	ASP98
C	ASP5
C	ASP98
E	ASP5
E	ASP98
G	ASP5
G	ASP98

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