Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP428 |
| A | ASN455 |
| A | THR457 |
| A | TPP602 |
| A | HOH786 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | binding site for residue TPP A 602 |
| Chain | Residue |
| A | GLY427 |
| A | ASP428 |
| A | GLY429 |
| A | SER430 |
| A | TYR433 |
| A | ASN455 |
| A | THR457 |
| A | TYR458 |
| A | GLY459 |
| A | MET460 |
| A | LEU461 |
| A | MG601 |
| A | HOH714 |
| A | HOH786 |
| A | HOH901 |
| B | ASN23 |
| B | PRO24 |
| B | GLY25 |
| B | GLU47 |
| B | HIS70 |
| B | ASN77 |
| A | THR377 |
| A | SER378 |
| A | GLY401 |
| A | LEU403 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | ASN117 |
| A | LEU118 |
| A | ARG120 |
| B | ASN117 |
| B | LEU118 |
| B | ARG120 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP428 |
| B | ASN455 |
| B | THR457 |
| B | TPP602 |
| B | HOH772 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | binding site for residue TPP B 602 |
| Chain | Residue |
| A | ASN23 |
| A | PRO24 |
| A | GLY25 |
| A | GLU47 |
| A | ASN77 |
| B | THR377 |
| B | SER378 |
| B | GLY401 |
| B | LEU403 |
| B | GLY427 |
| B | ASP428 |
| B | GLY429 |
| B | SER430 |
| B | TYR433 |
| B | ASN455 |
| B | THR457 |
| B | TYR458 |
| B | GLY459 |
| B | MET460 |
| B | LEU461 |
| B | MG601 |
| B | HOH712 |
| B | HOH772 |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. IGvqlaePerqvIaViGDGS |
| Chain | Residue | Details |
| A | ILE411-SER430 | |
