Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6A4U

The first crystal structure of crustacean ferritin that is a hybrid type of H and L ferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0004322	molecular_function	ferroxidase activity
B	0005737	cellular_component	cytoplasm
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0004322	molecular_function	ferroxidase activity
C	0005737	cellular_component	cytoplasm
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0004322	molecular_function	ferroxidase activity
D	0005737	cellular_component	cytoplasm
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
E	0004322	molecular_function	ferroxidase activity
E	0005737	cellular_component	cytoplasm
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
F	0004322	molecular_function	ferroxidase activity
F	0005737	cellular_component	cytoplasm
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue EDO A 201

Chain	Residue
A	TYR31
A	PHE51
A	SER55
A	GLU60
A	GLU106
A	SER143
A	HOH1029
A	HOH1059

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 202

Chain	Residue
A	LYS145
A	ASP149
A	HOH1060
A	HOH1067
A	HOH1148
A	GLU39

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 203

Chain	Residue
A	PHE51
A	GLU54
A	SER55
A	LYS146
A	HOH1059
A	HOH1117

site_id	AC4
Number of Residues	8
Details	binding site for residue EDO A 204

Chain	Residue
A	GLN82
A	HOH1028
A	HOH1039
D	GLN82
F	ASN22
F	TYR26
F	GLN82
F	ALA84

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 205

Chain	Residue
A	LYS153
A	TYR165
A	PHE167
A	GLU170
A	HOH1019
A	HOH1140

site_id	AC6
Number of Residues	5
Details	binding site for residue EDO A 206

Chain	Residue
A	GLY92
A	THR93
A	ARG156
A	GLU164
A	HOH1034

site_id	AC7
Number of Residues	4
Details	binding site for residue EDO A 207

Chain	Residue
A	LYS69
D	TYR36
D	GLU39
D	LYS53

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO A 208

Chain	Residue
A	LYS50
A	PHE51
A	GLU54
A	LEU171

site_id	AC9
Number of Residues	4
Details	binding site for residue EDO A 209

Chain	Residue
A	GLN99
A	ASP104
A	HOH1009
D	HOH328

site_id	AD1
Number of Residues	9
Details	binding site for residue SO4 A 210

Chain	Residue
A	SER87
A	MET88
A	ARG89
A	HOH1045
A	HOH1046
A	HOH1127
C	SER87
C	MET88
C	ARG89

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 A 211

Chain	Residue
A	SER28
A	TYR29
A	SER56
A	ARG61
D	SO4207

site_id	AD3
Number of Residues	5
Details	binding site for residue SO4 A 212

Chain	Residue
A	GLN7
A	ASN8
A	HOH1082
E	HOH305
E	HOH374

site_id	AD4
Number of Residues	9
Details	binding site for residue EDO B 201

Chain	Residue
B	TYR31
B	PHE51
B	SER55
B	GLU59
B	GLU60
B	GLU106
B	SER143
B	HOH308
B	HOH337

site_id	AD5
Number of Residues	4
Details	binding site for residue EDO B 202

Chain	Residue
B	LYS153
B	PHE167
B	GLU170
C	TYR165

site_id	AD6
Number of Residues	6
Details	binding site for residue EDO B 203

Chain	Residue
B	TYR165
D	LYS153
D	PHE167
D	GLU170
D	LEU171
D	HOH357

site_id	AD7
Number of Residues	7
Details	binding site for residue EDO B 204

Chain	Residue
B	PHE51
B	GLU54
B	SER55
B	GLU59
B	LYS146
B	HOH308
B	HOH388

site_id	AD8
Number of Residues	5
Details	binding site for residue EDO B 205

Chain	Residue
B	GLU164
D	ARG156
B	TYR37
B	LEU45
B	GLY92

site_id	AD9
Number of Residues	6
Details	binding site for residue EDO B 206

Chain	Residue
B	ASN18
B	LYS19
B	VAL79
B	GLN81
B	GLN81
B	HOH349

site_id	AE1
Number of Residues	5
Details	binding site for residue EDO B 207

Chain	Residue
B	LYS50
B	PHE51
B	GLU54
B	LEU171
B	ASN172

site_id	AE2
Number of Residues	5
Details	binding site for residue SO4 B 208

Chain	Residue
B	GLN7
B	ASN8
B	HOH328
B	HOH395
C	HOH311

site_id	AE3
Number of Residues	4
Details	binding site for residue SO4 B 209

Chain	Residue
B	MET88
B	ARG89
B	GLU90
B	HOH424

site_id	AE4
Number of Residues	6
Details	binding site for residue SO4 B 210

Chain	Residue
B	SER28
B	TYR29
B	SER56
E	LEU25
E	ARG61
E	SO4213

site_id	AE5
Number of Residues	5
Details	binding site for residue CL B 211

Chain	Residue
B	ALA84
B	ALA85
E	GLN82
E	MET88
E	ARG89

site_id	AE6
Number of Residues	7
Details	binding site for residue EDO C 201

Chain	Residue
C	TYR31
C	PHE51
C	SER55
C	GLU60
C	GLU106
C	SER143
C	HOH326

site_id	AE7
Number of Residues	6
Details	binding site for residue EDO C 202

Chain	Residue
C	PHE51
C	GLU54
C	SER55
C	GLU59
C	LYS146
C	HOH308

site_id	AE8
Number of Residues	6
Details	binding site for residue EDO C 203

Chain	Residue
B	HOH455
C	LYS145
C	ASP149
C	HOH339
C	HOH434
E	GLU39

site_id	AE9
Number of Residues	6
Details	binding site for residue EDO C 204

Chain	Residue
C	ALA157
C	GLY158
C	THR160
C	LEU162
C	GLY163
C	EDO207

site_id	AF1
Number of Residues	4
Details	binding site for residue EDO C 206

Chain	Residue
B	ARG156
C	LEU45
C	GLY92
C	GLU164

site_id	AF2
Number of Residues	7
Details	binding site for residue EDO C 207

Chain	Residue
C	ARG156
C	ALA157
C	EDO204
C	HOH316
E	GLY161
E	LEU162
E	HOH416

site_id	AF3
Number of Residues	6
Details	binding site for residue EDO C 208

Chain	Residue
C	LYS153
C	PHE167
C	GLU170
C	HOH436
E	TYR165
E	EDO211

site_id	AF4
Number of Residues	4
Details	binding site for residue EDO C 209

Chain	Residue
C	TYR9
C	HIS10
C	ASN123
C	HOH321

site_id	AF5
Number of Residues	5
Details	binding site for residue EDO C 210

Chain	Residue
C	HOH314
F	GLN99
F	ASP104
F	HOH305
F	HOH391

site_id	AF6
Number of Residues	6
Details	binding site for residue SO4 C 211

Chain	Residue
C	SER28
C	TYR29
C	SER56
C	ARG61
F	ARG61
F	SO4208

site_id	AF7
Number of Residues	3
Details	binding site for residue MG C 212

Chain	Residue
C	GLY158
C	PRO159
C	THR160

site_id	AF8
Number of Residues	1
Details	binding site for residue MG C 213

Chain	Residue
C	ASN8

site_id	AF9
Number of Residues	9
Details	binding site for residue EDO D 201

Chain	Residue
C	GLN82
D	ASN22
D	MET23
D	TYR26
D	GLN82
D	ALA84
D	HOH329
D	HOH347
F	GLN82

site_id	AG1
Number of Residues	8
Details	binding site for residue EDO D 202

Chain	Residue
D	TYR31
D	PHE51
D	SER55
D	GLU60
D	GLU106
D	SER143
D	HOH304
D	HOH343

site_id	AG2
Number of Residues	6
Details	binding site for residue EDO D 203

Chain	Residue
B	GLU39
D	LYS145
D	ASP149
D	HOH399
D	HOH409
D	HOH436

site_id	AG3
Number of Residues	7
Details	binding site for residue EDO D 204

Chain	Residue
D	PHE51
D	GLU54
D	SER55
D	GLU59
D	LYS146
D	HOH304
D	HOH317

site_id	AG4
Number of Residues	4
Details	binding site for residue EDO D 205

Chain	Residue
D	LEU45
D	GLY92
D	GLU164
E	ARG156

site_id	AG5
Number of Residues	3
Details	binding site for residue SO4 D 206

Chain	Residue
D	MET88
D	ARG89
D	GLU90

site_id	AG6
Number of Residues	5
Details	binding site for residue SO4 D 207

Chain	Residue
A	ARG61
A	SO4211
D	SER28
D	TYR29
D	ARG61

site_id	AG7
Number of Residues	4
Details	binding site for residue MG D 208

Chain	Residue
D	SER3
D	ARG6
D	GLY75
D	HOH440

site_id	AG8
Number of Residues	1
Details	binding site for residue MG D 209

Chain	Residue
D	ASN8

site_id	AG9
Number of Residues	8
Details	binding site for residue EDO E 201

Chain	Residue
E	TYR31
E	PHE51
E	SER55
E	GLU60
E	GLU106
E	SER143
E	HOH318
E	HOH327

site_id	AH1
Number of Residues	6
Details	binding site for residue EDO E 202

Chain	Residue
A	HOH1167
D	GLU39
E	LYS145
E	ASP149
E	HOH388
E	HOH426

site_id	AH2
Number of Residues	6
Details	binding site for residue EDO E 203

Chain	Residue
E	PHE51
E	GLU54
E	SER55
E	GLU59
E	LYS146
E	HOH327

site_id	AH3
Number of Residues	5
Details	binding site for residue EDO E 204

Chain	Residue
A	ASN124
E	LEU114
E	HIS117
E	SER118
E	SER121

site_id	AH4
Number of Residues	4
Details	binding site for residue EDO E 205

Chain	Residue
E	MET23
E	TYR26
E	HOH309
E	HOH331

site_id	AH5
Number of Residues	5
Details	binding site for residue EDO E 206

Chain	Residue
C	ARG156
E	LEU45
E	GLY92
E	THR93
E	GLU164

site_id	AH6
Number of Residues	4
Details	binding site for residue EDO E 207

Chain	Residue
D	TYR165
E	LYS153
E	PHE167
E	GLU170

site_id	AH7
Number of Residues	6
Details	binding site for residue EDO E 208

Chain	Residue
B	ARG40
E	ALA2
E	SER3
E	ARG77
E	HOH322
E	HOH393

site_id	AH8
Number of Residues	3
Details	binding site for residue EDO E 209

Chain	Residue
E	ASP12
E	ALA15
E	EDO210

site_id	AH9
Number of Residues	3
Details	binding site for residue EDO E 210

Chain	Residue
E	ASP12
E	SER16
E	EDO209

site_id	AI1
Number of Residues	4
Details	binding site for residue EDO E 212

Chain	Residue
E	TYR26
E	SER87
E	TRP91
E	HOH392

site_id	AI2
Number of Residues	8
Details	binding site for residue SO4 E 213

Chain	Residue
B	LEU25
B	ARG61
B	SO4210
E	LEU25
E	SER28
E	TYR29
E	SER56
E	ARG61

site_id	AI3
Number of Residues	5
Details	binding site for residue SO4 E 214

Chain	Residue
D	HOH314
E	GLN7
E	ASN8
E	HOH412
E	HOH422

site_id	AI4
Number of Residues	8
Details	binding site for residue EDO F 201

Chain	Residue
F	TYR31
F	PHE51
F	SER55
F	GLU60
F	GLU106
F	SER143
F	HOH307
F	HOH330

site_id	AI5
Number of Residues	7
Details	binding site for residue EDO F 203

Chain	Residue
F	PHE51
F	GLU54
F	SER55
F	GLU59
F	LYS146
F	HOH307
F	HOH308

site_id	AI6
Number of Residues	5
Details	binding site for residue EDO F 204

Chain	Residue
C	ASN124
C	PRO126
F	LEU114
F	HIS117
F	SER118

site_id	AI7
Number of Residues	5
Details	binding site for residue EDO F 205

Chain	Residue
F	LYS153
F	TYR165
F	PHE167
F	GLU170
F	HOH332

site_id	AI8
Number of Residues	7
Details	binding site for residue EDO F 206

Chain	Residue
A	SER87
F	ALA15
F	ASN18
F	GLN81
F	HOH304
F	HOH311
F	HOH386

site_id	AI9
Number of Residues	5
Details	binding site for residue EDO F 207

Chain	Residue
F	TYR37
F	LEU45
F	GLY92
F	ARG156
F	GLU164

site_id	AJ1
Number of Residues	5
Details	binding site for residue SO4 F 208

Chain	Residue
C	ARG61
C	SO4211
F	SER28
F	TYR29
F	SER56

site_id	AJ2
Number of Residues	3
Details	binding site for residue SO4 F 209

Chain	Residue
F	MET88
F	ARG89
F	GLU90

site_id	AJ3
Number of Residues	2
Details	binding site for residue MG F 210

Chain	Residue
F	ASN8
F	HOH460

site_id	AJ4
Number of Residues	17
Details	binding site for Di-peptide EDO C 205 and GLU C 39

Chain	Residue
B	LYS145
B	ASP149
C	ALA35
C	TYR36
C	TYR37
C	PHE38
C	ARG40
C	ASP41
C	ALA49
C	LYS53
C	HOH301
C	HOH312
C	HOH318
C	HOH344
C	HOH359
C	HOH435
F	ASN72

site_id	AJ5
Number of Residues	13
Details	binding site for Di-peptide EDO E 211 and LYS E 169

Chain	Residue
C	LYS153
C	GLU170
C	EDO208
C	HOH437
E	TYR165
E	MET166
E	PHE167
E	ASP168
E	GLU170
E	LEU171
E	ASN172
E	HOH302
E	HOH411

site_id	AJ6
Number of Residues	18
Details	binding site for Di-peptide EDO F 202 and GLU F 39

Chain	Residue
C	LYS69
C	ASN72
F	ALA35
F	TYR36
F	TYR37
F	PHE38
F	ARG40
F	ASP41
F	LYS53
F	LYS145
F	LYS145
F	ASP149
F	HOH301
F	HOH309
F	HOH337
F	HOH434
F	HOH447
F	HOH457

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)