6A4U
The first crystal structure of crustacean ferritin that is a hybrid type of H and L ferritin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004322 | molecular_function | ferroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0006880 | biological_process | intracellular sequestering of iron ion |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004322 | molecular_function | ferroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006826 | biological_process | iron ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0006880 | biological_process | intracellular sequestering of iron ion |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004322 | molecular_function | ferroxidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006826 | biological_process | iron ion transport |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0006880 | biological_process | intracellular sequestering of iron ion |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0008199 | molecular_function | ferric iron binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004322 | molecular_function | ferroxidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006826 | biological_process | iron ion transport |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0006880 | biological_process | intracellular sequestering of iron ion |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0008199 | molecular_function | ferric iron binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004322 | molecular_function | ferroxidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006826 | biological_process | iron ion transport |
| E | 0006879 | biological_process | intracellular iron ion homeostasis |
| E | 0006880 | biological_process | intracellular sequestering of iron ion |
| E | 0008198 | molecular_function | ferrous iron binding |
| E | 0008199 | molecular_function | ferric iron binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004322 | molecular_function | ferroxidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006826 | biological_process | iron ion transport |
| F | 0006879 | biological_process | intracellular iron ion homeostasis |
| F | 0006880 | biological_process | intracellular sequestering of iron ion |
| F | 0008198 | molecular_function | ferrous iron binding |
| F | 0008199 | molecular_function | ferric iron binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | TYR31 |
| A | PHE51 |
| A | SER55 |
| A | GLU60 |
| A | GLU106 |
| A | SER143 |
| A | HOH1029 |
| A | HOH1059 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | LYS145 |
| A | ASP149 |
| A | HOH1060 |
| A | HOH1067 |
| A | HOH1148 |
| A | GLU39 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | PHE51 |
| A | GLU54 |
| A | SER55 |
| A | LYS146 |
| A | HOH1059 |
| A | HOH1117 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 204 |
| Chain | Residue |
| A | GLN82 |
| A | HOH1028 |
| A | HOH1039 |
| D | GLN82 |
| F | ASN22 |
| F | TYR26 |
| F | GLN82 |
| F | ALA84 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 205 |
| Chain | Residue |
| A | LYS153 |
| A | TYR165 |
| A | PHE167 |
| A | GLU170 |
| A | HOH1019 |
| A | HOH1140 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 206 |
| Chain | Residue |
| A | GLY92 |
| A | THR93 |
| A | ARG156 |
| A | GLU164 |
| A | HOH1034 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 207 |
| Chain | Residue |
| A | LYS69 |
| D | TYR36 |
| D | GLU39 |
| D | LYS53 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 208 |
| Chain | Residue |
| A | LYS50 |
| A | PHE51 |
| A | GLU54 |
| A | LEU171 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 209 |
| Chain | Residue |
| A | GLN99 |
| A | ASP104 |
| A | HOH1009 |
| D | HOH328 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 210 |
| Chain | Residue |
| A | SER87 |
| A | MET88 |
| A | ARG89 |
| A | HOH1045 |
| A | HOH1046 |
| A | HOH1127 |
| C | SER87 |
| C | MET88 |
| C | ARG89 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 211 |
| Chain | Residue |
| A | SER28 |
| A | TYR29 |
| A | SER56 |
| A | ARG61 |
| D | SO4207 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 212 |
| Chain | Residue |
| A | GLN7 |
| A | ASN8 |
| A | HOH1082 |
| E | HOH305 |
| E | HOH374 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| B | TYR31 |
| B | PHE51 |
| B | SER55 |
| B | GLU59 |
| B | GLU60 |
| B | GLU106 |
| B | SER143 |
| B | HOH308 |
| B | HOH337 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| B | LYS153 |
| B | PHE167 |
| B | GLU170 |
| C | TYR165 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | TYR165 |
| D | LYS153 |
| D | PHE167 |
| D | GLU170 |
| D | LEU171 |
| D | HOH357 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 204 |
| Chain | Residue |
| B | PHE51 |
| B | GLU54 |
| B | SER55 |
| B | GLU59 |
| B | LYS146 |
| B | HOH308 |
| B | HOH388 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | GLU164 |
| D | ARG156 |
| B | TYR37 |
| B | LEU45 |
| B | GLY92 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 206 |
| Chain | Residue |
| B | ASN18 |
| B | LYS19 |
| B | VAL79 |
| B | GLN81 |
| B | GLN81 |
| B | HOH349 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 207 |
| Chain | Residue |
| B | LYS50 |
| B | PHE51 |
| B | GLU54 |
| B | LEU171 |
| B | ASN172 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 208 |
| Chain | Residue |
| B | GLN7 |
| B | ASN8 |
| B | HOH328 |
| B | HOH395 |
| C | HOH311 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 209 |
| Chain | Residue |
| B | MET88 |
| B | ARG89 |
| B | GLU90 |
| B | HOH424 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 210 |
| Chain | Residue |
| B | SER28 |
| B | TYR29 |
| B | SER56 |
| E | LEU25 |
| E | ARG61 |
| E | SO4213 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 211 |
| Chain | Residue |
| B | ALA84 |
| B | ALA85 |
| E | GLN82 |
| E | MET88 |
| E | ARG89 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 201 |
| Chain | Residue |
| C | TYR31 |
| C | PHE51 |
| C | SER55 |
| C | GLU60 |
| C | GLU106 |
| C | SER143 |
| C | HOH326 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 202 |
| Chain | Residue |
| C | PHE51 |
| C | GLU54 |
| C | SER55 |
| C | GLU59 |
| C | LYS146 |
| C | HOH308 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 203 |
| Chain | Residue |
| B | HOH455 |
| C | LYS145 |
| C | ASP149 |
| C | HOH339 |
| C | HOH434 |
| E | GLU39 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 204 |
| Chain | Residue |
| C | ALA157 |
| C | GLY158 |
| C | THR160 |
| C | LEU162 |
| C | GLY163 |
| C | EDO207 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 206 |
| Chain | Residue |
| B | ARG156 |
| C | LEU45 |
| C | GLY92 |
| C | GLU164 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 207 |
| Chain | Residue |
| C | ARG156 |
| C | ALA157 |
| C | EDO204 |
| C | HOH316 |
| E | GLY161 |
| E | LEU162 |
| E | HOH416 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 208 |
| Chain | Residue |
| C | LYS153 |
| C | PHE167 |
| C | GLU170 |
| C | HOH436 |
| E | TYR165 |
| E | EDO211 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 209 |
| Chain | Residue |
| C | TYR9 |
| C | HIS10 |
| C | ASN123 |
| C | HOH321 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 210 |
| Chain | Residue |
| C | HOH314 |
| F | GLN99 |
| F | ASP104 |
| F | HOH305 |
| F | HOH391 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 211 |
| Chain | Residue |
| C | SER28 |
| C | TYR29 |
| C | SER56 |
| C | ARG61 |
| F | ARG61 |
| F | SO4208 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 212 |
| Chain | Residue |
| C | GLY158 |
| C | PRO159 |
| C | THR160 |
| site_id | AF8 |
| Number of Residues | 1 |
| Details | binding site for residue MG C 213 |
| Chain | Residue |
| C | ASN8 |
| site_id | AF9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| C | GLN82 |
| D | ASN22 |
| D | MET23 |
| D | TYR26 |
| D | GLN82 |
| D | ALA84 |
| D | HOH329 |
| D | HOH347 |
| F | GLN82 |
| site_id | AG1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 202 |
| Chain | Residue |
| D | TYR31 |
| D | PHE51 |
| D | SER55 |
| D | GLU60 |
| D | GLU106 |
| D | SER143 |
| D | HOH304 |
| D | HOH343 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 203 |
| Chain | Residue |
| B | GLU39 |
| D | LYS145 |
| D | ASP149 |
| D | HOH399 |
| D | HOH409 |
| D | HOH436 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 204 |
| Chain | Residue |
| D | PHE51 |
| D | GLU54 |
| D | SER55 |
| D | GLU59 |
| D | LYS146 |
| D | HOH304 |
| D | HOH317 |
| site_id | AG4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 205 |
| Chain | Residue |
| D | LEU45 |
| D | GLY92 |
| D | GLU164 |
| E | ARG156 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 206 |
| Chain | Residue |
| D | MET88 |
| D | ARG89 |
| D | GLU90 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 207 |
| Chain | Residue |
| A | ARG61 |
| A | SO4211 |
| D | SER28 |
| D | TYR29 |
| D | ARG61 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 208 |
| Chain | Residue |
| D | SER3 |
| D | ARG6 |
| D | GLY75 |
| D | HOH440 |
| site_id | AG8 |
| Number of Residues | 1 |
| Details | binding site for residue MG D 209 |
| Chain | Residue |
| D | ASN8 |
| site_id | AG9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO E 201 |
| Chain | Residue |
| E | TYR31 |
| E | PHE51 |
| E | SER55 |
| E | GLU60 |
| E | GLU106 |
| E | SER143 |
| E | HOH318 |
| E | HOH327 |
| site_id | AH1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 202 |
| Chain | Residue |
| A | HOH1167 |
| D | GLU39 |
| E | LYS145 |
| E | ASP149 |
| E | HOH388 |
| E | HOH426 |
| site_id | AH2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 203 |
| Chain | Residue |
| E | PHE51 |
| E | GLU54 |
| E | SER55 |
| E | GLU59 |
| E | LYS146 |
| E | HOH327 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 204 |
| Chain | Residue |
| A | ASN124 |
| E | LEU114 |
| E | HIS117 |
| E | SER118 |
| E | SER121 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 205 |
| Chain | Residue |
| E | MET23 |
| E | TYR26 |
| E | HOH309 |
| E | HOH331 |
| site_id | AH5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 206 |
| Chain | Residue |
| C | ARG156 |
| E | LEU45 |
| E | GLY92 |
| E | THR93 |
| E | GLU164 |
| site_id | AH6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 207 |
| Chain | Residue |
| D | TYR165 |
| E | LYS153 |
| E | PHE167 |
| E | GLU170 |
| site_id | AH7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 208 |
| Chain | Residue |
| B | ARG40 |
| E | ALA2 |
| E | SER3 |
| E | ARG77 |
| E | HOH322 |
| E | HOH393 |
| site_id | AH8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 209 |
| Chain | Residue |
| E | ASP12 |
| E | ALA15 |
| E | EDO210 |
| site_id | AH9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 210 |
| Chain | Residue |
| E | ASP12 |
| E | SER16 |
| E | EDO209 |
| site_id | AI1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 212 |
| Chain | Residue |
| E | TYR26 |
| E | SER87 |
| E | TRP91 |
| E | HOH392 |
| site_id | AI2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 E 213 |
| Chain | Residue |
| B | LEU25 |
| B | ARG61 |
| B | SO4210 |
| E | LEU25 |
| E | SER28 |
| E | TYR29 |
| E | SER56 |
| E | ARG61 |
| site_id | AI3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 E 214 |
| Chain | Residue |
| D | HOH314 |
| E | GLN7 |
| E | ASN8 |
| E | HOH412 |
| E | HOH422 |
| site_id | AI4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO F 201 |
| Chain | Residue |
| F | TYR31 |
| F | PHE51 |
| F | SER55 |
| F | GLU60 |
| F | GLU106 |
| F | SER143 |
| F | HOH307 |
| F | HOH330 |
| site_id | AI5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 203 |
| Chain | Residue |
| F | PHE51 |
| F | GLU54 |
| F | SER55 |
| F | GLU59 |
| F | LYS146 |
| F | HOH307 |
| F | HOH308 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 204 |
| Chain | Residue |
| C | ASN124 |
| C | PRO126 |
| F | LEU114 |
| F | HIS117 |
| F | SER118 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 205 |
| Chain | Residue |
| F | LYS153 |
| F | TYR165 |
| F | PHE167 |
| F | GLU170 |
| F | HOH332 |
| site_id | AI8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 206 |
| Chain | Residue |
| A | SER87 |
| F | ALA15 |
| F | ASN18 |
| F | GLN81 |
| F | HOH304 |
| F | HOH311 |
| F | HOH386 |
| site_id | AI9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 207 |
| Chain | Residue |
| F | TYR37 |
| F | LEU45 |
| F | GLY92 |
| F | ARG156 |
| F | GLU164 |
| site_id | AJ1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 F 208 |
| Chain | Residue |
| C | ARG61 |
| C | SO4211 |
| F | SER28 |
| F | TYR29 |
| F | SER56 |
| site_id | AJ2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 209 |
| Chain | Residue |
| F | MET88 |
| F | ARG89 |
| F | GLU90 |
| site_id | AJ3 |
| Number of Residues | 2 |
| Details | binding site for residue MG F 210 |
| Chain | Residue |
| F | ASN8 |
| F | HOH460 |
| site_id | AJ4 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide EDO C 205 and GLU C 39 |
| Chain | Residue |
| B | LYS145 |
| B | ASP149 |
| C | ALA35 |
| C | TYR36 |
| C | TYR37 |
| C | PHE38 |
| C | ARG40 |
| C | ASP41 |
| C | ALA49 |
| C | LYS53 |
| C | HOH301 |
| C | HOH312 |
| C | HOH318 |
| C | HOH344 |
| C | HOH359 |
| C | HOH435 |
| F | ASN72 |
| site_id | AJ5 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide EDO E 211 and LYS E 169 |
| Chain | Residue |
| C | LYS153 |
| C | GLU170 |
| C | EDO208 |
| C | HOH437 |
| E | TYR165 |
| E | MET166 |
| E | PHE167 |
| E | ASP168 |
| E | GLU170 |
| E | LEU171 |
| E | ASN172 |
| E | HOH302 |
| E | HOH411 |
| site_id | AJ6 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide EDO F 202 and GLU F 39 |
| Chain | Residue |
| C | LYS69 |
| C | ASN72 |
| F | ALA35 |
| F | TYR36 |
| F | TYR37 |
| F | PHE38 |
| F | ARG40 |
| F | ASP41 |
| F | LYS53 |
| F | LYS145 |
| F | LYS145 |
| F | ASP149 |
| F | HOH301 |
| F | HOH309 |
| F | HOH337 |
| F | HOH434 |
| F | HOH447 |
| F | HOH457 |
