6A35

Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form II

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009086	biological_process	methionine biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
A	0044237	biological_process	cellular metabolic process
A	0044249	biological_process	cellular biosynthetic process
A	0046523	molecular_function	S-methyl-5-thioribose-1-phosphate isomerase activity
B	0009086	biological_process	methionine biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
B	0044237	biological_process	cellular metabolic process
B	0044249	biological_process	cellular biosynthetic process
B	0046523	molecular_function	S-methyl-5-thioribose-1-phosphate isomerase activity
C	0009086	biological_process	methionine biosynthetic process
C	0016853	molecular_function	isomerase activity
C	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
C	0044237	biological_process	cellular metabolic process
C	0044249	biological_process	cellular biosynthetic process
C	0046523	molecular_function	S-methyl-5-thioribose-1-phosphate isomerase activity
D	0009086	biological_process	methionine biosynthetic process
D	0016853	molecular_function	isomerase activity
D	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
D	0044237	biological_process	cellular metabolic process
D	0044249	biological_process	cellular biosynthetic process
D	0046523	molecular_function	S-methyl-5-thioribose-1-phosphate isomerase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01678

Chain	Residue	Details
A	ASP247
B	ASP247
C	ASP247
D	ASP247

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site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01678

Chain	Residue	Details
A	ARG57
C	ARG100
C	GLN206
C	ASN257
D	ARG57
D	ARG100
D	GLN206
D	ASN257
A	ARG100
A	GLN206
A	ASN257
B	ARG57
B	ARG100
B	GLN206
B	ASN257
C	ARG57

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01678

Chain	Residue	Details
A	CYS167
B	CYS167
C	CYS167
D	CYS167

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