Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004712 | molecular_function | protein serine/threonine/tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0046777 | biological_process | protein autophosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 801 |
| Chain | Residue |
| A | LYS167 |
| A | PHE479 |
| A | LYS480 |
| A | LYS481 |
| A | HOH1030 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | LYS264 |
| A | ARG300 |
| A | SER301 |
| A | HOH1038 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | ASN365 |
| A | GLU366 |
| A | VAL367 |
| A | LYS393 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 804 |
| Chain | Residue |
| A | SER169 |
| A | LYS193 |
| A | LYS194 |
| A | HOH969 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 805 |
| Chain | Residue |
| A | ASN232 |
| A | ARG325 |
| A | ARG328 |
| A | GLU366 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 806 |
| Chain | Residue |
| A | ARG226 |
| A | HOH940 |
| A | HOH1041 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue 9OF A 807 |
| Chain | Residue |
| A | LYS167 |
| A | PHE170 |
| A | VAL173 |
| A | ALA186 |
| A | PHE238 |
| A | GLU239 |
| A | LEU241 |
| A | LEU294 |
| A | PGE808 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue PGE A 808 |
| Chain | Residue |
| A | LYS188 |
| A | GLU203 |
| A | PHE238 |
| A | ASN244 |
| A | GLU291 |
| A | ASN292 |
| A | LEU294 |
| A | VAL306 |
| A | ASP307 |
| A | 9OF807 |
| A | HOH921 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGQVVkAydrveqew..........VAIK |
| Chain | Residue | Details |
| A | ILE165-LYS188 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHcDLKpeNILL |
| Chain | Residue | Details |
| A | ILE283-LEU295 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"23665168","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"23665168","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"UniProtKB","id":"Q63470","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"23665168","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"23665168","evidenceCode":"ECO:0000269"}]} |
