6A10
Crystal structure of hen egg white lysozyme crystallized by ammonium sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005783 | cellular_component | endoplasmic reticulum |
| C | 0005794 | cellular_component | Golgi apparatus |
| C | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0050829 | biological_process | defense response to Gram-negative bacterium |
| C | 0050830 | biological_process | defense response to Gram-positive bacterium |
| C | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ARG14 |
| A | HIS15 |
| A | HOH333 |
| A | HOH347 |
| B | GLY4 |
| B | ARG5 |
| B | CYS6 |
| B | GLU7 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | HOH301 |
| A | HOH302 |
| C | ARG114 |
| A | ASN74 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | GLY71 |
| A | ARG73 |
| A | HOH316 |
| A | HOH351 |
| A | HOH376 |
| C | ASN37 |
| C | HOH391 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | PHE34 |
| A | ARG114 |
| A | HOH303 |
| A | HOH310 |
| A | HOH384 |
| A | HOH391 |
| B | ASN74 |
| B | HOH416 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | ARG14 |
| B | HIS15 |
| B | HOH353 |
| B | HOH370 |
| B | HOH374 |
| B | HOH380 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| A | ASN37 |
| B | GLY71 |
| B | ARG73 |
| B | HOH304 |
| B | HOH322 |
| B | HOH323 |
| B | HOH348 |
| B | HOH399 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | ARG114 |
| B | HOH311 |
| C | ASN74 |
| C | HOH341 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | ARG5 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 C 202 |
| Chain | Residue |
| A | GLY4 |
| A | ARG5 |
| A | CYS6 |
| A | GLU7 |
| C | ARG14 |
| C | HIS15 |
| C | HOH328 |
| C | HOH363 |
| C | HOH368 |
| C | HOH434 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 203 |
| Chain | Residue |
| B | GLN41 |
| C | ARG125 |
| C | GLY126 |
| C | CYS127 |
| C | ARG128 |
| C | HOH312 |
| C | HOH355 |
| C | HOH407 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| A | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 384 |
| Details | Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| A | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN46 | |
| A | ASP48 | |
| A | SER50 | |
| A | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| A | ASN59 |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| B | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ASN46 | |
| B | ASP48 | |
| B | SER50 | |
| B | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| B | ASN59 |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| C | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | ASN46 | |
| C | ASP48 | |
| C | SER50 | |
| C | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| C | ASN59 |
