5ZZ6
Redox-sensing transcriptional repressor Rex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0051775 | biological_process | response to redox state |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0051775 | biological_process | response to redox state |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| C | 0051775 | biological_process | response to redox state |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0051775 | biological_process | response to redox state |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue NAD A 301 |
| Chain | Residue |
| A | GLY91 |
| A | HIS157 |
| A | ILE161 |
| A | PHE176 |
| A | ALA177 |
| A | PRO178 |
| A | ILE192 |
| A | THR193 |
| B | ALA96 |
| B | VAL97 |
| B | TYR100 |
| A | ASN92 |
| A | ILE93 |
| A | ASP115 |
| A | SER116 |
| A | LYS120 |
| A | ALA152 |
| A | VAL153 |
| A | PRO154 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue NAD B 301 |
| Chain | Residue |
| A | ALA96 |
| A | VAL97 |
| A | TYR100 |
| B | VAL88 |
| B | GLY89 |
| B | ALA90 |
| B | GLY91 |
| B | ASN92 |
| B | ILE93 |
| B | ASP115 |
| B | SER116 |
| B | ASP117 |
| B | LYS120 |
| B | ALA152 |
| B | VAL153 |
| B | PRO154 |
| B | HIS157 |
| B | ILE161 |
| B | PHE176 |
| B | ALA177 |
| B | PRO178 |
| B | ILE192 |
| B | HOH410 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue ADP C 301 |
| Chain | Residue |
| C | GLY91 |
| C | ASN92 |
| C | ILE93 |
| C | ASP115 |
| C | SER116 |
| C | ASP117 |
| C | LYS120 |
| C | VAL153 |
| C | PRO154 |
| C | HIS157 |
| D | TYR100 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue NAD D 301 |
| Chain | Residue |
| C | ALA96 |
| C | TYR100 |
| D | GLY89 |
| D | GLY91 |
| D | ASN92 |
| D | ILE93 |
| D | ASP115 |
| D | SER116 |
| D | ASP117 |
| D | LYS120 |
| D | VAL134 |
| D | ALA152 |
| D | VAL153 |
| D | PRO154 |
| D | ALA155 |
| D | HIS157 |
| D | PHE176 |
| D | ALA177 |
| D | PRO178 |
| D | ILE192 |
| D | HOH413 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 117 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"HAMAP-Rule","id":"MF_01131","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01131","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
