5ZZ6
Redox-sensing transcriptional repressor Rex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
A | 0051775 | biological_process | response to redox state |
B | 0003677 | molecular_function | DNA binding |
B | 0003700 | molecular_function | DNA-binding transcription factor activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
B | 0051775 | biological_process | response to redox state |
C | 0003677 | molecular_function | DNA binding |
C | 0003700 | molecular_function | DNA-binding transcription factor activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006355 | biological_process | regulation of DNA-templated transcription |
C | 0045892 | biological_process | negative regulation of DNA-templated transcription |
C | 0051775 | biological_process | response to redox state |
D | 0003677 | molecular_function | DNA binding |
D | 0003700 | molecular_function | DNA-binding transcription factor activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006355 | biological_process | regulation of DNA-templated transcription |
D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
D | 0051775 | biological_process | response to redox state |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | binding site for residue NAD A 301 |
Chain | Residue |
A | GLY91 |
A | HIS157 |
A | ILE161 |
A | PHE176 |
A | ALA177 |
A | PRO178 |
A | ILE192 |
A | THR193 |
B | ALA96 |
B | VAL97 |
B | TYR100 |
A | ASN92 |
A | ILE93 |
A | ASP115 |
A | SER116 |
A | LYS120 |
A | ALA152 |
A | VAL153 |
A | PRO154 |
site_id | AC2 |
Number of Residues | 23 |
Details | binding site for residue NAD B 301 |
Chain | Residue |
A | ALA96 |
A | VAL97 |
A | TYR100 |
B | VAL88 |
B | GLY89 |
B | ALA90 |
B | GLY91 |
B | ASN92 |
B | ILE93 |
B | ASP115 |
B | SER116 |
B | ASP117 |
B | LYS120 |
B | ALA152 |
B | VAL153 |
B | PRO154 |
B | HIS157 |
B | ILE161 |
B | PHE176 |
B | ALA177 |
B | PRO178 |
B | ILE192 |
B | HOH410 |
site_id | AC3 |
Number of Residues | 11 |
Details | binding site for residue ADP C 301 |
Chain | Residue |
C | GLY91 |
C | ASN92 |
C | ILE93 |
C | ASP115 |
C | SER116 |
C | ASP117 |
C | LYS120 |
C | VAL153 |
C | PRO154 |
C | HIS157 |
D | TYR100 |
site_id | AC4 |
Number of Residues | 21 |
Details | binding site for residue NAD D 301 |
Chain | Residue |
C | ALA96 |
C | TYR100 |
D | GLY89 |
D | GLY91 |
D | ASN92 |
D | ILE93 |
D | ASP115 |
D | SER116 |
D | ASP117 |
D | LYS120 |
D | VAL134 |
D | ALA152 |
D | VAL153 |
D | PRO154 |
D | ALA155 |
D | HIS157 |
D | PHE176 |
D | ALA177 |
D | PRO178 |
D | ILE192 |
D | HOH413 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 156 |
Details | DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_01131 |
Chain | Residue | Details |
A | SER15-PHE54 | |
B | SER15-PHE54 | |
C | SER15-PHE54 | |
D | SER15-PHE54 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01131 |
Chain | Residue | Details |
A | GLY89 | |
B | GLY89 | |
C | GLY89 | |
D | GLY89 |