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5ZYT

Crystal structure of human MGME1 with 3' overhang double strand DNA3

Functional Information from GO Data
ChainGOidnamespacecontents
A0004518molecular_functionnuclease activity
A0004527molecular_functionexonuclease activity
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005759cellular_componentmitochondrial matrix
A0006264biological_processmitochondrial DNA replication
A0006281biological_processDNA repair
A0006974biological_processDNA damage response
A0008297molecular_functionsingle-stranded DNA exodeoxyribonuclease activity
A0016787molecular_functionhydrolase activity
A0017108molecular_function5'-flap endonuclease activity
A0043504biological_processmitochondrial DNA repair
A0045145molecular_functionsingle-stranded DNA 5'-3' DNA exonuclease activity
B0004518molecular_functionnuclease activity
B0004527molecular_functionexonuclease activity
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005759cellular_componentmitochondrial matrix
B0006264biological_processmitochondrial DNA replication
B0006281biological_processDNA repair
B0006974biological_processDNA damage response
B0008297molecular_functionsingle-stranded DNA exodeoxyribonuclease activity
B0016787molecular_functionhydrolase activity
B0017108molecular_function5'-flap endonuclease activity
B0043504biological_processmitochondrial DNA repair
B0045145molecular_functionsingle-stranded DNA 5'-3' DNA exonuclease activity
C0004518molecular_functionnuclease activity
C0004527molecular_functionexonuclease activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005759cellular_componentmitochondrial matrix
C0006264biological_processmitochondrial DNA replication
C0006281biological_processDNA repair
C0006974biological_processDNA damage response
C0008297molecular_functionsingle-stranded DNA exodeoxyribonuclease activity
C0016787molecular_functionhydrolase activity
C0017108molecular_function5'-flap endonuclease activity
C0043504biological_processmitochondrial DNA repair
C0045145molecular_functionsingle-stranded DNA 5'-3' DNA exonuclease activity
D0004518molecular_functionnuclease activity
D0004527molecular_functionexonuclease activity
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005759cellular_componentmitochondrial matrix
D0006264biological_processmitochondrial DNA replication
D0006281biological_processDNA repair
D0006974biological_processDNA damage response
D0008297molecular_functionsingle-stranded DNA exodeoxyribonuclease activity
D0016787molecular_functionhydrolase activity
D0017108molecular_function5'-flap endonuclease activity
D0043504biological_processmitochondrial DNA repair
D0045145molecular_functionsingle-stranded DNA 5'-3' DNA exonuclease activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsActive site: {"evidences":[{"source":"PubMed","id":"23358826","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

247947

PDB entries from 2026-01-21

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