5ZQT

Crystal structure of Oryza sativa hexokinase 6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001678	biological_process	intracellular glucose homeostasis
A	0004340	molecular_function	glucokinase activity
A	0004396	molecular_function	hexokinase activity
A	0005524	molecular_function	ATP binding
A	0005536	molecular_function	D-glucose binding
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006006	biological_process	glucose metabolic process
A	0006096	biological_process	glycolytic process
A	0008865	molecular_function	fructokinase activity
A	0009507	cellular_component	chloroplast
A	0009527	cellular_component	plastid outer membrane
A	0009536	cellular_component	plastid
A	0009707	cellular_component	chloroplast outer membrane
A	0009749	biological_process	response to glucose
A	0016020	cellular_component	membrane
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019318	biological_process	hexose metabolic process
A	0046835	biological_process	carbohydrate phosphorylation
A	0051156	biological_process	glucose 6-phosphate metabolic process
B	0000166	molecular_function	nucleotide binding
B	0001678	biological_process	intracellular glucose homeostasis
B	0004340	molecular_function	glucokinase activity
B	0004396	molecular_function	hexokinase activity
B	0005524	molecular_function	ATP binding
B	0005536	molecular_function	D-glucose binding
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006006	biological_process	glucose metabolic process
B	0006096	biological_process	glycolytic process
B	0008865	molecular_function	fructokinase activity
B	0009507	cellular_component	chloroplast
B	0009527	cellular_component	plastid outer membrane
B	0009536	cellular_component	plastid
B	0009707	cellular_component	chloroplast outer membrane
B	0009749	biological_process	response to glucose
B	0016020	cellular_component	membrane
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0019318	biological_process	hexose metabolic process
B	0046835	biological_process	carbohydrate phosphorylation
B	0051156	biological_process	glucose 6-phosphate metabolic process
C	0000166	molecular_function	nucleotide binding
C	0001678	biological_process	intracellular glucose homeostasis
C	0004340	molecular_function	glucokinase activity
C	0004396	molecular_function	hexokinase activity
C	0005524	molecular_function	ATP binding
C	0005536	molecular_function	D-glucose binding
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006006	biological_process	glucose metabolic process
C	0006096	biological_process	glycolytic process
C	0008865	molecular_function	fructokinase activity
C	0009507	cellular_component	chloroplast
C	0009527	cellular_component	plastid outer membrane
C	0009536	cellular_component	plastid
C	0009707	cellular_component	chloroplast outer membrane
C	0009749	biological_process	response to glucose
C	0016020	cellular_component	membrane
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019318	biological_process	hexose metabolic process
C	0046835	biological_process	carbohydrate phosphorylation
C	0051156	biological_process	glucose 6-phosphate metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00378
Number of Residues	26
Details	HEXOKINASE_1 Hexokinase domain signature. LGFTFSFPvhqtsISsgtLikWTKgF

Chain	Residue	Details
A	LEU180-PHE205

---

site_id	PS00782
Number of Residues	16
Details	TFIIB Transcription factor TFIIB repeat signature. GRyvdNDVAAAVILGT

Chain	Residue	Details
A	GLY246-THR261

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	414
Details	Region: {"description":"Hexokinase small subdomain","evidences":[{"source":"PROSITE-ProRule","id":"PRU01084","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31176485","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6JJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JJ9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31176485","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6JJ8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31176485","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2018","submissionDatabase":"PDB data bank","title":"Crystal structure of Oryza sativa hexokinase 6.","authors":["Matsudaira K.","Mochizuki S.","Yoshida H.","Kamitori S.","Akimitsu K."]}},{"source":"PDB","id":"5ZQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JJ7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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