5ZQK
Dengue Virus Non Structural Protein 5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| A | 0004483 | molecular_function | methyltransferase cap1 activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| B | 0004483 | molecular_function | methyltransferase cap1 activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SAM A 1001 |
| Chain | Residue |
| A | SER56 |
| A | HIS110 |
| A | VAL130 |
| A | ASP131 |
| A | VAL132 |
| A | PHE133 |
| A | ASP146 |
| A | HOH1101 |
| A | HOH1107 |
| A | HOH1178 |
| A | HOH1295 |
| A | GLY58 |
| A | HOH1342 |
| A | GLY81 |
| A | CYS82 |
| A | GLY83 |
| A | GLY86 |
| A | TRP87 |
| A | THR104 |
| A | LYS105 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1002 |
| Chain | Residue |
| A | ALA473 |
| A | TRP475 |
| A | ASP539 |
| A | ARG599 |
| A | GLY600 |
| A | SER601 |
| A | THR606 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1003 |
| Chain | Residue |
| A | HIS712 |
| A | HIS714 |
| A | CYS728 |
| A | CYS847 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1004 |
| Chain | Residue |
| A | GLU438 |
| A | HIS442 |
| A | CYS447 |
| A | CYS450 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | GLY203 |
| A | ALA224 |
| A | HOH1110 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue SAM B 1001 |
| Chain | Residue |
| B | SER56 |
| B | GLY58 |
| B | GLY81 |
| B | CYS82 |
| B | GLY83 |
| B | GLY86 |
| B | TRP87 |
| B | THR104 |
| B | LYS105 |
| B | HIS110 |
| B | VAL130 |
| B | ASP131 |
| B | VAL132 |
| B | PHE133 |
| B | ASP146 |
| B | HOH1104 |
| B | HOH1108 |
| B | HOH1249 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 1002 |
| Chain | Residue |
| B | TRP475 |
| B | ASP539 |
| B | ARG599 |
| B | GLY600 |
| B | SER601 |
| B | THR606 |
| B | HOH1105 |
| B | HOH1127 |
| B | HOH1159 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 1003 |
| Chain | Residue |
| B | ASP534 |
| B | ASP664 |
| B | MG1004 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 1004 |
| Chain | Residue |
| B | ALA532 |
| B | ASP534 |
| B | MG1003 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1005 |
| Chain | Residue |
| B | GLU438 |
| B | HIS442 |
| B | CYS447 |
| B | CYS450 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1006 |
| Chain | Residue |
| B | HIS712 |
| B | HIS714 |
| B | CYS728 |
| B | CYS847 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 1007 |
| Chain | Residue |
| B | SER230 |
| B | ASN233 |
| B | ARG237 |
