5ZNP

Crystal structure of PtSHL in complex with an H3K4me3 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0046872	molecular_function	metal ion binding
B	0003682	molecular_function	chromatin binding
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	CYS142
A	CYS144
A	HIS165
A	CYS168

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 502

Chain	Residue
A	CYS157
A	CYS160
A	CYS184
A	CYS187

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 501

Chain	Residue
B	CYS144
B	HIS165
B	CYS168
B	CYS142

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN B 502

Chain	Residue
B	CYS157
B	CYS160
B	CYS184
B	CYS187

---

Functional Information from PROSITE/UniProt

site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CkCemPYnpddlmvqC

Chain	Residue	Details
A	CYS142-CYS157

---

site_id	PS01359
Number of Residues	46
Details	ZF_PHD_1 Zinc finger PHD-type signature. Ck.Cempynpddlm...................................VqCeg..Csdw.FHpaCiemsaeeakrldh................................FfCenC

Chain	Residue	Details
A	CYS142-CYS187

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Not N6-methylated => ECO:0000269|PubMed:15598823

Chain	Residue	Details
P	LYS14
Q	LYS14

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:12581305, ECO:0000269|PubMed:14712277, ECO:0000269|PubMed:15598823, ECO:0000269|PubMed:16258034

Chain	Residue	Details
P	M3L4
Q	M3L4

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:12456661, ECO:0000269|PubMed:12581305, ECO:0000269|PubMed:14712277, ECO:0000269|PubMed:15014946, ECO:0000269|PubMed:15598823

Chain	Residue	Details
P	LYS9
Q	LYS9

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:14610360, ECO:0000269|PubMed:15753571

Chain	Residue	Details
P	SER10
Q	SER10

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:15753571

Chain	Residue	Details
P	THR11
Q	THR11

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:15598823, ECO:0000269|PubMed:16648464, ECO:0000269|PubMed:17174094, ECO:0000269|PubMed:17363895

Chain	Residue	Details
P	LYS14
Q	LYS14

---