5ZK9
Stapled-peptides tailored against initiation of translation
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue MGP A 1001 |
| Chain | Residue |
| A | LYS54 |
| A | HOH1104 |
| A | HOH1118 |
| A | HOH1126 |
| A | HOH1131 |
| A | HOH1136 |
| A | HOH1154 |
| A | HOH1197 |
| A | THR55 |
| A | TRP56 |
| A | MET101 |
| A | TRP102 |
| A | GLU103 |
| A | ARG157 |
| A | LYS162 |
| A | HOH1102 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 1002 |
| Chain | Residue |
| A | THR116 |
| A | GLN121 |
| A | VAL194 |
| A | ILE195 |
| A | HOH1117 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue PEG A 1003 |
| Chain | Residue |
| A | GLN40 |
| A | ASN41 |
| A | ASN118 |
| A | GLN121 |
| A | SER124 |
| A | ASP147 |
| A | HOH1151 |
| A | HOH1164 |
| B | ARG2 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 1004 |
| Chain | Residue |
| A | ARG42 |
| A | ASP96 |
| A | LYS119 |
| A | GLN120 |
| A | ARG122 |
| A | ARG123 |
| A | HOH1113 |
| A | HOH1123 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residues MK8 B 8 and MK8 B 12 |
| Chain | Residue |
| B | SER6 |
| B | ARG7 |
| B | GLN9 |
| B | LEU10 |
| B | LEU11 |
| B | LEU13 |
| B | LYS14 |
| B | NH215 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKdgIePmWEDeknkrGGRW |
| Chain | Residue | Details |
| A | ASP90-TRP113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Region: {"description":"EIF4EBP1/2/3 binding","evidences":[{"source":"PubMed","id":"16271312","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11879179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12975586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16271312","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"(Microbial infection) Interaction with potato virus Y VPg","evidences":[{"source":"PubMed","id":"31712417","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
