5ZHQ
Crystal structure of Scylla paramamosain arginine kinase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004054 | molecular_function | arginine kinase activity |
| A | 0004111 | molecular_function | creatine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0019863 | molecular_function | IgE binding |
| A | 0046314 | biological_process | phosphocreatine biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004054 | molecular_function | arginine kinase activity |
| B | 0004111 | molecular_function | creatine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005615 | cellular_component | extracellular space |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0019863 | molecular_function | IgE binding |
| B | 0046314 | biological_process | phosphocreatine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ARG124 |
| A | ARG126 |
| A | ARG229 |
| A | ARG280 |
| B | HIS315 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG202 |
| A | TYR203 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | GLN241 |
| A | ARG244 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | VAL111 |
| A | ASN112 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | HIS315 |
| B | ARG124 |
| B | ARG126 |
| B | ARG229 |
| B | ARG280 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | GLN241 |
| B | ARG244 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | ARG202 |
| B | TYR203 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide SO4 B 404 and ARG B 280 |
| Chain | Residue |
| A | HIS315 |
| B | ARG124 |
| B | VAL125 |
| B | ARG126 |
| B | VAL279 |
| B | ALA281 |
| B | GLN307 |
| B | ARG309 |
| B | ASP324 |
| B | ASN327 |
| B | ARG330 |
| B | SO4401 |
Functional Information from PROSITE/UniProt
| site_id | PS00112 |
| Number of Residues | 7 |
| Details | PHOSPHAGEN_KINASE Phosphagen kinase active site signature. CP.TNLGT |
| Chain | Residue | Details |
| A | CYS271-THR277 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 164 |
| Details | Domain: {"description":"Phosphagen kinase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00842","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 474 |
| Details | Domain: {"description":"Phosphagen kinase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00843","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00843","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 56 |
| Details | Region: {"description":"IgE-binding and beta-hexosaminidase release from rat basophilic leukemia (RBL) cells","evidences":[{"source":"PubMed","id":"25728640","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 56 |
| Details | Region: {"description":"IgE-binding and beta-hexosaminidase release from rat basophilic leukemia (RBL) cells","evidences":[{"source":"PubMed","id":"23911402","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25728640","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 28 |
| Details | Region: {"description":"IgE-binding, but no beta-hexosaminidase release from rat basophilic leukemia (RBL) cells","evidences":[{"source":"PubMed","id":"23911402","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25728640","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 28 |
| Details | Region: {"description":"IgE-binding, but no beta-hexosaminidase release from rat basophilic leukemia (RBL) cells","evidences":[{"source":"PubMed","id":"25728640","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q004B5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
