Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5ZEA

Crystal structure of the nucleotide-free mutant A3B3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0006814	biological_process	sodium ion transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046034	biological_process	ATP metabolic process
A	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0006814	biological_process	sodium ion transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046034	biological_process	ATP metabolic process
B	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0006814	biological_process	sodium ion transport
C	0035725	biological_process	sodium ion transmembrane transport
C	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046034	biological_process	ATP metabolic process
C	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0006814	biological_process	sodium ion transport
D	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0006814	biological_process	sodium ion transport
E	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0006814	biological_process	sodium ion transport
F	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0006814	biological_process	sodium ion transport
G	0035725	biological_process	sodium ion transmembrane transport
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	0046034	biological_process	ATP metabolic process
G	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0006814	biological_process	sodium ion transport
H	0035725	biological_process	sodium ion transmembrane transport
H	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	0046034	biological_process	ATP metabolic process
H	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0006814	biological_process	sodium ion transport
I	0035725	biological_process	sodium ion transmembrane transport
I	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0046034	biological_process	ATP metabolic process
I	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0006814	biological_process	sodium ion transport
J	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
J	0046034	biological_process	ATP metabolic process
J	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0006814	biological_process	sodium ion transport
K	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
K	0046034	biological_process	ATP metabolic process
K	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
K	1902600	biological_process	proton transmembrane transport
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0006814	biological_process	sodium ion transport
L	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
L	0046034	biological_process	ATP metabolic process
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 601

Chain	Residue
A	ASP140
A	THR142
A	LYS143
A	ILE144
A	ILE145
A	GLN146

site_id	AC2
Number of Residues	2
Details	binding site for residue GOL A 602

Chain	Residue
A	ASN204
A	GLU440

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 603

Chain	Residue
A	ASP134
A	ILE135
A	SER377
A	ASP378
A	ILE124

site_id	AC4
Number of Residues	1
Details	binding site for residue GOL A 604

Chain	Residue
A	GLU177

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 605

Chain	Residue
A	LYS224
A	ASP250
A	ASP252
A	ASP323
A	GOL606

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL A 606

Chain	Residue
A	VAL207
A	LYS224
A	ASP323
A	ARG371
A	GLU381
A	GOL605

site_id	AC7
Number of Residues	3
Details	binding site for residue GOL C 601

Chain	Residue
C	GLY321
C	GLU381
C	HOH703

site_id	AC8
Number of Residues	2
Details	binding site for residue GOL D 501

Chain	Residue
D	PHE177
D	ARG206

site_id	AC9
Number of Residues	1
Details	binding site for residue GOL D 503

Chain	Residue
D	LYS452

site_id	AD1
Number of Residues	3
Details	binding site for residue GOL D 504

Chain	Residue
D	ALA435
D	GOL505
F	LYS66

site_id	AD2
Number of Residues	5
Details	binding site for residue GOL D 505

Chain	Residue
D	ILE400
D	MET436
D	GOL504
F	LYS66
F	ASN67

site_id	AD3
Number of Residues	2
Details	binding site for residue GOL G 601

Chain	Residue
G	THR168
G	ASP171

site_id	AD4
Number of Residues	2
Details	binding site for residue GOL G 602

Chain	Residue
G	GLY321
G	GLU381

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL G 603

Chain	Residue
G	ASP140
G	THR142
G	LYS143
G	ILE144
G	GLN146

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL H 601

Chain	Residue
H	GLN244
H	LYS247
H	LEU276
H	PHE506

site_id	AD7
Number of Residues	3
Details	binding site for residue GOL K 501

Chain	Residue
B	GLU96
K	ALA435
K	LEU437

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PPIDVLPSLS

Chain	Residue	Details
D	PRO340-SER349
A	PRO426-SER435

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY232
B	GLY232
C	GLY232
G	GLY232
H	GLY232
I	GLY232

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)