5ZE6

CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH BPH-981

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004659	molecular_function	prenyltransferase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006744	biological_process	ubiquinone biosynthetic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0106350	molecular_function	all-trans-octaprenyl-diphosphate synthase activity
B	0004659	molecular_function	prenyltransferase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006744	biological_process	ubiquinone biosynthetic process
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0106350	molecular_function	all-trans-octaprenyl-diphosphate synthase activity
C	0004659	molecular_function	prenyltransferase activity
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006744	biological_process	ubiquinone biosynthetic process
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016094	biological_process	polyprenol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0106350	molecular_function	all-trans-octaprenyl-diphosphate synthase activity
D	0004659	molecular_function	prenyltransferase activity
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0006744	biological_process	ubiquinone biosynthetic process
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016094	biological_process	polyprenol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding
D	0106350	molecular_function	all-trans-octaprenyl-diphosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue HJX A 401

Chain	Residue
A	HIS77
C	TYR116
A	THR80
A	LEU81
A	ASP84
A	ARG93
A	ASP113
A	GLU146
A	HOH529
C	ASP113

---

site_id	AC2
Number of Residues	8
Details	binding site for residue HJX B 401

Chain	Residue
B	THR80
B	LEU81
B	ASP84
B	ASP113
B	GLU146
B	HOH502
D	ASP113
D	TYR116

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG B 402

Chain	Residue
B	ASP84
B	ASP88
B	GLU146
B	HOH502
B	HOH504

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG B 403

Chain	Residue
B	ASP84
B	ASP88
B	HOH502

---

Functional Information from PROSITE/UniProt

site_id	PS00444
Number of Residues	13
Details	POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. LGtaFQLiDDLlD

Chain	Residue	Details
A	LEU203-ASP215

---

site_id	PS00723
Number of Residues	15
Details	POLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LLhDDvv..DesdmRRG

Chain	Residue	Details
A	LEU81-GLY95

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P14324","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q12051","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---