5ZCW
Structure of the Methanosarcina mazei class II CPD-photolyase in complex with intact, phosphodiester linked, CPD-lesion
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000719 | biological_process | photoreactive repair |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003904 | molecular_function | deoxyribodipyrimidine photo-lyase activity |
| A | 0003913 | molecular_function | DNA photolyase activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0009650 | biological_process | UV protection |
| A | 0016829 | molecular_function | lyase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000719 | biological_process | photoreactive repair |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003904 | molecular_function | deoxyribodipyrimidine photo-lyase activity |
| B | 0003913 | molecular_function | DNA photolyase activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0009650 | biological_process | UV protection |
| B | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | GLY65 |
| A | HOH664 |
| A | ILE66 |
| A | ARG67 |
| A | ARG215 |
| A | ALA216 |
| A | PHE225 |
| A | ARG405 |
| A | HOH613 |
| A | HOH626 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | binding site for residue FAD A 502 |
| Chain | Residue |
| A | TYR252 |
| A | LEU264 |
| A | SER265 |
| A | ASN266 |
| A | LEU267 |
| A | SER268 |
| A | LEU271 |
| A | GLU301 |
| A | ILE302 |
| A | TRP305 |
| A | LYS306 |
| A | SER309 |
| A | LYS372 |
| A | GLY375 |
| A | ARG378 |
| A | MET379 |
| A | ALA382 |
| A | ASN403 |
| A | ASP409 |
| A | GLY410 |
| A | ASN414 |
| A | GLY415 |
| A | SER422 |
| A | HOH631 |
| A | HOH646 |
| A | HOH656 |
| A | HOH660 |
| A | HOH672 |
| C | TTD7 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| A | PRO-2 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | binding site for residue FAD B 501 |
| Chain | Residue |
| B | TYR252 |
| B | LEU264 |
| B | SER265 |
| B | ASN266 |
| B | SER268 |
| B | LEU271 |
| B | GLU301 |
| B | ILE302 |
| B | TRP305 |
| B | LYS306 |
| B | SER309 |
| B | LYS372 |
| B | GLY375 |
| B | ARG378 |
| B | MET379 |
| B | ALA382 |
| B | ASN403 |
| B | ASP409 |
| B | GLY410 |
| B | ASN414 |
| B | GLY415 |
| B | ILE419 |
| B | SER422 |
| B | HOH606 |
| E | TTD7 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for Di-nucleotide DC E 6 and TTD E 7 |
| Chain | Residue |
| B | ALA160 |
| B | HIS161 |
| B | ARG256 |
| B | ASN257 |
| B | GLU301 |
| B | TRP305 |
| B | MET379 |
| B | TRP421 |
| B | ARG429 |
| B | TRP431 |
| B | ARG441 |
| B | FAD501 |
| B | HOH606 |
| E | DG5 |
| E | DC8 |
| E | HOH102 |
| F | DA8 |
| F | DG9 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | binding site for Di-nucleotide TTD E 7 and DC E 8 |
| Chain | Residue |
| E | DG9 |
| E | HOH102 |
| F | DG6 |
| B | ALA160 |
| B | HIS161 |
| B | ARG256 |
| B | ASN257 |
| B | GLU301 |
| B | TRP305 |
| B | TYR376 |
| B | MET379 |
| B | TRP421 |
| B | TRP431 |
| B | ARG441 |
| B | TYR442 |
| B | MET443 |
| B | FAD501 |
| B | HOH606 |
| E | DC6 |
