5Z5A
Crystal structure of Tk-PTP in the active form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016311 | biological_process | dephosphorylation |
| C | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue VN3 A 201 |
| Chain | Residue |
| A | ASP63 |
| A | HOH308 |
| C | ARG117 |
| A | CYS93 |
| A | MET94 |
| A | GLY95 |
| A | GLY96 |
| A | LEU97 |
| A | GLY98 |
| A | ARG99 |
| A | GLU132 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue VN3 B 201 |
| Chain | Residue |
| A | ARG117 |
| B | ASP63 |
| B | CYS93 |
| B | MET94 |
| B | GLY95 |
| B | GLY96 |
| B | LEU97 |
| B | GLY98 |
| B | ARG99 |
| B | GLU132 |
| B | HOH303 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue VN3 C 201 |
| Chain | Residue |
| B | ARG117 |
| C | ASP63 |
| C | CYS93 |
| C | MET94 |
| C | GLY95 |
| C | GLY96 |
| C | LEU97 |
| C | GLY98 |
| C | ARG99 |
| C | GLU132 |
| C | HOH319 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCmgGlgRSG |
| Chain | Residue | Details |
| A | ILE91-GLY101 |
