Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
A | 0009085 | biological_process | lysine biosynthetic process |
A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016726 | molecular_function | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor |
A | 0019877 | biological_process | diaminopimelate biosynthetic process |
A | 0050661 | molecular_function | NADP binding |
A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 33 |
Details | binding site for residue NAP A 301 |
Chain | Residue |
A | GLY8 |
A | LEU75 |
A | THR76 |
A | THR77 |
A | GLN80 |
A | GLY98 |
A | THR99 |
A | THR100 |
A | ALA124 |
A | PRO125 |
A | ASN126 |
A | ARG10 |
A | PHE127 |
A | LYS158 |
A | PDC302 |
A | HOH418 |
A | HOH425 |
A | HOH430 |
A | HOH434 |
A | HOH447 |
A | HOH453 |
A | HOH455 |
A | GLY11 |
A | HOH463 |
A | HOH464 |
A | HOH467 |
A | HOH476 |
A | LYS12 |
A | MET13 |
A | LEU33 |
A | ASP34 |
A | HIS35 |
A | LYS36 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue PDC A 302 |
Chain | Residue |
A | THR100 |
A | PRO125 |
A | ASN126 |
A | HIS154 |
A | HIS155 |
A | LYS158 |
A | SER163 |
A | GLY164 |
A | THR165 |
A | PHE239 |
A | NAP301 |
A | HOH425 |
A | HOH453 |
A | HOH481 |
Functional Information from PROSITE/UniProt
site_id | PS01298 |
Number of Residues | 18 |
Details | DAPB Dihydrodipicolinate reductase signature. EIiEmHhdqKlDapSGTA |
Chain | Residue | Details |
A | GLU149-ALA166 | |