5YWS

Crystal structure of TREX1 in complex with a Y structured DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008408	molecular_function	3'-5' exonuclease activity
B	0003676	molecular_function	nucleic acid binding
B	0008408	molecular_function	3'-5' exonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 301

Chain	Residue
A	ASP18
A	GLU20
A	ASP200
A	MG302
C	DC22

---

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 302

Chain	Residue
A	HOH526
C	DT21
C	DC22
A	ASP18
A	MG301
A	HOH417
A	HOH465

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG B 301

Chain	Residue
B	ASP18
B	GLU20
B	ASP200
B	MG302
D	DC22

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MG B 302

Chain	Residue
B	ASP18
B	MG301
B	HOH424
B	HOH447
B	HOH542
D	DT21
D	DC22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17293595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780819","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22071149","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9NSU2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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