5YW7

Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000166	molecular_function	nucleotide binding
B	0005267	molecular_function	potassium channel activity
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0008281	molecular_function	sulfonylurea receptor activity
B	0008282	cellular_component	inward rectifying potassium channel
B	0009410	biological_process	response to xenobiotic stimulus
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
B	0032991	cellular_component	protein-containing complex
B	0035774	biological_process	positive regulation of insulin secretion involved in cellular response to glucose stimulus
B	0042383	cellular_component	sarcolemma
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0043531	molecular_function	ADP binding
B	0044325	molecular_function	transmembrane transporter binding
B	0046676	biological_process	negative regulation of insulin secretion
B	0046872	molecular_function	metal ion binding
B	0055085	biological_process	transmembrane transport
B	0071805	biological_process	potassium ion transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue GBM B 2001

site_id	AC2
Number of Residues	9
Details	binding site for residue AGS B 2002

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRISVARAL