5YW4

Structure-Guided Engineering of Reductase: Efficient Attenuating Substrate Inhibition in Asymmetric Catalysis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0045551	molecular_function	cinnamyl-alcohol dehydrogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	binding site for residue NAP A 401

Chain	Residue
A	THR11
A	PRO83
A	VAL84
A	THR123
A	SER124
A	SER125
A	TYR163
A	LYS167
A	PRO192
A	VAL193
A	ASN210
A	GLY12
A	SER212
A	HOH501
A	HOH520
A	HOH545
A	HOH559
A	HOH560
A	HOH593
A	HOH634
A	TYR13
A	LEU14
A	ARG34
A	LYS38
A	LEU58
A	THR80
A	SER82

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