5YW0

Crystal structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase in complex with succinate and Fe(III)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue PG4 A 401

Chain	Residue
A	GLY179
A	LEU193
A	TYR220
A	GLN240
A	VAL241
A	LEU295
A	HOH574

---

site_id	AC2
Number of Residues	3
Details	binding site for residue PG4 A 402

Chain	Residue
A	HOH627
A	HIS109
A	TYR205

---

site_id	AC3
Number of Residues	7
Details	binding site for residue PG4 A 403

Chain	Residue
A	ARG76
A	ALA122
A	ARG123
A	ARG162
A	THR272
A	HIS274
A	HOH513

---

site_id	AC4
Number of Residues	2
Details	binding site for residue PG4 A 404

Chain	Residue
A	TYR213
A	HOH505

---

site_id	AC5
Number of Residues	1
Details	binding site for residue PG4 A 405

Chain	Residue
A	GLN15

---

site_id	AC6
Number of Residues	6
Details	binding site for residue FE A 406

Chain	Residue
A	HIS146
A	ASP148
A	HIS260
A	SIN408
A	HOH501
A	HOH509

---

site_id	AC7
Number of Residues	7
Details	binding site for residue GOL A 407

Chain	Residue
A	PRO12
A	GLY40
A	GLY179
A	GLU180
A	VAL258
A	LEU259
A	HOH553

---

site_id	AC8
Number of Residues	13
Details	binding site for residue SIN A 408

Chain	Residue
A	ARG127
A	ASP142
A	HIS146
A	ARG162
A	ARG174
A	TRP176
A	HIS260
A	VAL262
A	FE406
A	ACT409
A	HOH501
A	HOH509
A	HOH510

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ACT A 409

Chain	Residue
A	PHE150
A	ARG162
A	SIN408
A	HOH509

---

site_id	AD1
Number of Residues	5
Details	binding site for residue ACT A 410

Chain	Residue
A	GLY156
A	LEU288
A	GLU303
A	HOH503
A	HOH514

---

site_id	AD2
Number of Residues	1
Details	binding site for residue ACT A 411

Chain	Residue
A	ARG214

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ACT A 412

Chain	Residue
A	LYS276
A	ASN278
A	SER304
A	HOH514

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30092253","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5YW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30092253","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5Y9I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5Y9X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5Y9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30092253","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5Y9X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YVZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30092253","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5Y9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Important for activity","evidences":[{"source":"PubMed","id":"30092253","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---