5YS3
1.8 angstrom crystal structure of Succinate-Acetate Permease from Citrobacter koseri
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015360 | molecular_function | acetate:proton symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0035433 | biological_process | acetate transmembrane transport |
| A | 0071422 | biological_process | succinate transmembrane transport |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015360 | molecular_function | acetate:proton symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0035433 | biological_process | acetate transmembrane transport |
| B | 0071422 | biological_process | succinate transmembrane transport |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0015360 | molecular_function | acetate:proton symporter activity |
| C | 0016020 | cellular_component | membrane |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0035433 | biological_process | acetate transmembrane transport |
| C | 0071422 | biological_process | succinate transmembrane transport |
| C | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | LEU24 |
| A | ASN28 |
| A | LEU138 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 202 |
| Chain | Residue |
| A | PHE135 |
| A | PHE17 |
| A | THR21 |
| A | LEU24 |
| A | ASN25 |
| A | TRP76 |
| A | LEU134 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 203 |
| Chain | Residue |
| A | PHE17 |
| A | GLN50 |
| A | PHE69 |
| A | TYR72 |
| A | ACT204 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 204 |
| Chain | Residue |
| A | PHE64 |
| A | GLY65 |
| A | PHE69 |
| A | ACT203 |
| A | HOH322 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 205 |
| Chain | Residue |
| A | PHE52 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 206 |
| Chain | Residue |
| A | LYS5 |
| A | LEU6 |
| A | LYS60 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue PLM A 207 |
| Chain | Residue |
| A | ALA123 |
| A | SER163 |
| A | TYR166 |
| A | GLY185 |
| A | PLM210 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue PLM A 208 |
| Chain | Residue |
| A | LYS87 |
| B | GLY89 |
| B | GLU92 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue PLM A 210 |
| Chain | Residue |
| A | TYR166 |
| A | PLM207 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue 78M A 211 |
| Chain | Residue |
| A | GLY107 |
| A | VAL108 |
| A | ALA136 |
| A | PHE140 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue 78M A 212 |
| Chain | Residue |
| A | ALA81 |
| A | MET88 |
| A | LEU90 |
| C | ILE43 |
| C | PHE44 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 201 |
| Chain | Residue |
| A | LEU189 |
| B | LEU24 |
| B | ASN28 |
| B | LEU138 |
| B | ASN142 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 202 |
| Chain | Residue |
| B | PHE17 |
| B | THR21 |
| B | ASN25 |
| B | TRP76 |
| B | LEU134 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 203 |
| Chain | Residue |
| B | LEU14 |
| B | PHE17 |
| B | GLN50 |
| B | PHE69 |
| B | TYR72 |
| B | ACT204 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 204 |
| Chain | Residue |
| B | PHE64 |
| B | GLY65 |
| B | PHE69 |
| B | LEU124 |
| B | ACT203 |
| B | HOH311 |
| B | HOH312 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 205 |
| Chain | Residue |
| B | LEU55 |
| B | LYS59 |
| B | HOH303 |
| B | HOH326 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 206 |
| Chain | Residue |
| B | GLN176 |
| B | HOH304 |
| C | PHE64 |
| C | ALA120 |
| C | LEU124 |
| C | HOH302 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue PLM B 207 |
| Chain | Residue |
| A | ILE181 |
| B | 78M214 |
| B | 78M214 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue PLM B 208 |
| Chain | Residue |
| B | ILE165 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue PLM B 209 |
| Chain | Residue |
| B | GLY107 |
| B | THR132 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue 78M B 211 |
| Chain | Residue |
| B | ILE43 |
| B | PHE44 |
| C | ILE43 |
| C | MET85 |
| C | MET88 |
| C | LEU90 |
| site_id | AE4 |
| Number of Residues | 1 |
| Details | binding site for residue 78M B 212 |
| Chain | Residue |
| B | MET88 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue 78M B 213 |
| Chain | Residue |
| B | ALA123 |
| B | SER163 |
| B | PRO183 |
| B | GLY185 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue 78M B 214 |
| Chain | Residue |
| A | ILE181 |
| B | PHE112 |
| B | PHE115 |
| B | PLM207 |
| B | PLM207 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue ACT C 201 |
| Chain | Residue |
| C | HOH335 |
| C | ASN28 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 202 |
| Chain | Residue |
| C | PHE17 |
| C | THR21 |
| C | ASN25 |
| C | TRP76 |
| C | LEU134 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue ACT C 203 |
| Chain | Residue |
| C | GLY13 |
| C | PHE17 |
| C | GLN50 |
| C | PHE69 |
| C | TYR72 |
| C | ACT204 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue ACT C 204 |
| Chain | Residue |
| C | PHE64 |
| C | GLY65 |
| C | PHE69 |
| C | LEU124 |
| C | ACT203 |
| C | HOH302 |
| C | HOH319 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue ACT C 205 |
| Chain | Residue |
| C | TYR58 |
| C | LYS59 |
| C | HOH322 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue ACT C 206 |
| Chain | Residue |
| A | ILE51 |
| C | ILE48 |
| C | HOH318 |
| site_id | AF4 |
| Number of Residues | 1 |
| Details | binding site for residue PLM C 207 |
| Chain | Residue |
| C | ILE181 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue PLM C 208 |
| Chain | Residue |
| C | GLY107 |
| C | ALA136 |
| C | ILE143 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue 78M C 209 |
| Chain | Residue |
| C | VAL159 |
| C | ALA162 |
| C | SER163 |
Functional Information from PROSITE/UniProt
| site_id | PS01114 |
| Number of Residues | 10 |
| Details | GPR1_FUN34_YAAH GPR1/FUN34/yaaH family signature. NPAPLGLmGF |
| Chain | Residue | Details |
| A | ASN8-PHE17 |
