5YOF
Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 7HS B 201 |
| Chain | Residue |
| A | SER81 |
| B | GLY151 |
| B | ASN152 |
| B | GLY153 |
| B | TYR161 |
| B | HOH305 |
| B | HOH323 |
| A | GLY82 |
| A | ASP83 |
| B | HIS51 |
| B | ASP75 |
| B | ASP129 |
| B | TYR130 |
| B | ALA132 |
| B | SER135 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"PubMed","id":"29080786","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29526431","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
