5YJH
Structural insights into periostin functions
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 701 |
| Chain | Residue |
| A | ASN583 |
| A | HOH818 |
| A | HOH839 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 702 |
| Chain | Residue |
| A | SER67 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 703 |
| Chain | Residue |
| A | THR59 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 704 |
| Chain | Residue |
| A | LYS172 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 705 |
| Chain | Residue |
| A | GLY82 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 706 |
| Chain | Residue |
| A | GLN422 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 707 |
| Chain | Residue |
| A | GLN479 |
| A | LEU440 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 708 |
| Chain | Residue |
| A | LYS497 |
| A | LYS502 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 709 |
| Chain | Residue |
| A | GLU78 |
| A | CYS79 |
| A | ARG85 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 710 |
| Chain | Residue |
| A | MET316 |
| A | GLY317 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 713 |
| Chain | Residue |
| A | ARG173 |
| A | TYR462 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 716 |
| Chain | Residue |
| A | LYS172 |
| A | ASN441 |
| A | GLN479 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 718 |
| Chain | Residue |
| A | LEU50 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 719 |
| Chain | Residue |
| A | SER131 |
| A | ARG173 |
| A | THR219 |
| A | GLY221 |
| A | LEU443 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 720 |
| Chain | Residue |
| A | ILE98 |
| A | ASP99 |
| A | THR104 |
| A | ILE217 |
| A | HOH861 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 721 |
| Chain | Residue |
| A | ARG458 |
| A | GLY529 |
| A | ASP530 |
| A | THR617 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 722 |
| Chain | Residue |
| A | ALA110 |
| A | THR112 |
| A | THR113 |
| A | PRO137 |
| A | SER138 |
| A | ASN139 |
| A | TRP142 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 723 |
| Chain | Residue |
| A | PHE250 |
| A | PRO274 |
| A | THR275 |
| A | PHE279 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 724 |
| Chain | Residue |
| A | GLN380 |
| A | GLN381 |
| A | PHE384 |
| A | PRO408 |
| A | VAL409 |
| A | ASN410 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 725 |
| Chain | Residue |
| A | PHE509 |
| A | THR511 |
| A | PHE512 |
| A | PRO536 |
| A | ASN538 |
| A | PHE541 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 726 |
| Chain | Residue |
| A | CYS208 |
| A | ARG228 |
| A | CYS311 |
| A | SER312 |
| A | GLU313 |
| A | ASP350 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 727 |
| Chain | Residue |
| A | GLY574 |
| A | GLU597 |
| A | LEU602 |
| A | SER612 |
| A | ASP613 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 728 |
| Chain | Residue |
| A | PHE195 |
| A | ASN197 |
| A | THR205 |
| A | ASN207 |
| A | CYS208 |
| A | CYS311 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 729 |
| Chain | Residue |
| A | HOH929 |
| A | HOH949 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 730 |
| Chain | Residue |
| A | ASN445 |
| A | VAL571 |
| A | HOH813 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue ZN A 732 |
| Chain | Residue |
| A | LYS586 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 54 |
| Details | Domain: {"description":"EMI","evidences":[{"source":"PROSITE-ProRule","id":"PRU00384","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 133 |
| Details | Domain: {"description":"FAS1 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 131 |
| Details | Domain: {"description":"FAS1 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 124 |
| Details | Domain: {"description":"FAS1 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 132 |
| Details | Domain: {"description":"FAS1 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cysteinyl cysteine","evidences":[{"source":"PubMed","id":"29754429","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
