5YJG
Structural insights into periostin functions
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 701 |
| Chain | Residue |
| A | TYR462 |
| A | PHE577 |
| A | ASN583 |
| A | HOH881 |
| A | HOH957 |
| A | HOH1071 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CYS A 702 |
| Chain | Residue |
| A | TYR64 |
| A | ASP38 |
| A | GLN39 |
| A | CYS60 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 703 |
| Chain | Residue |
| A | GLY318 |
| A | HOH1129 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 704 |
| Chain | Residue |
| A | HOH1085 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 705 |
| Chain | Residue |
| A | LYS592 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 706 |
| Chain | Residue |
| A | GLU78 |
| A | CYS79 |
| A | ARG85 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 707 |
| Chain | Residue |
| A | ARG123 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 709 |
| Chain | Residue |
| A | ARG173 |
| A | ALA218 |
| A | GLY221 |
| A | HOH849 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 712 |
| Chain | Residue |
| A | LYS502 |
| A | GLN505 |
| A | HOH1146 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 713 |
| Chain | Residue |
| A | ARG173 |
| A | TYR462 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 716 |
| Chain | Residue |
| A | LYS66 |
| A | SER67 |
| A | LYS72 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 717 |
| Chain | Residue |
| A | GLN422 |
| A | HOH1057 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CA A 719 |
| Chain | Residue |
| A | ASP258 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 720 |
| Chain | Residue |
| A | LYS379 |
| A | HOH1037 |
| A | HOH1079 |
| A | HOH1124 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 721 |
| Chain | Residue |
| A | HOH809 |
| A | HOH923 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 722 |
| Chain | Residue |
| A | THR176 |
| A | HOH1122 |
| A | HOH1177 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 723 |
| Chain | Residue |
| A | VAL571 |
| A | HOH824 |
| A | HOH1069 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 724 |
| Chain | Residue |
| A | HOH913 |
| A | HOH1194 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 725 |
| Chain | Residue |
| A | ALA110 |
| A | THR112 |
| A | THR113 |
| A | PRO137 |
| A | SER138 |
| A | ASN139 |
| A | TRP142 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 726 |
| Chain | Residue |
| A | ASP246 |
| A | LEU247 |
| A | PHE250 |
| A | PRO274 |
| A | THR275 |
| A | ASN276 |
| A | PHE279 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 727 |
| Chain | Residue |
| A | GLN380 |
| A | GLN381 |
| A | PHE384 |
| A | PRO408 |
| A | VAL409 |
| A | ASN410 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 728 |
| Chain | Residue |
| A | PHE509 |
| A | THR511 |
| A | PHE512 |
| A | PRO536 |
| A | ASN538 |
| A | PHE541 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 729 |
| Chain | Residue |
| A | CYS208 |
| A | ARG228 |
| A | CYS311 |
| A | SER312 |
| A | GLU313 |
| A | ASP350 |
| site_id | AE6 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 730 |
| Chain | Residue |
| A | HOH830 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 731 |
| Chain | Residue |
| A | GLY574 |
| A | GLU597 |
| A | SER612 |
| A | ASP613 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 732 |
| Chain | Residue |
| A | PHE195 |
| A | ASN197 |
| A | THR205 |
| A | ASN207 |
| A | CYS208 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue ZN A 733 |
| Chain | Residue |
| A | LYS586 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 54 |
| Details | Domain: {"description":"EMI","evidences":[{"source":"PROSITE-ProRule","id":"PRU00384","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 133 |
| Details | Domain: {"description":"FAS1 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 131 |
| Details | Domain: {"description":"FAS1 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 124 |
| Details | Domain: {"description":"FAS1 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 132 |
| Details | Domain: {"description":"FAS1 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cysteinyl cysteine","evidences":[{"source":"PubMed","id":"29754429","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
