Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 A 501 |
| Chain | Residue |
| A | HIS381 |
| e | EF2501 |
| A | SER382 |
| A | TRP383 |
| A | TRP389 |
| A | TRP403 |
| A | PHE405 |
| A | HOH603 |
| e | THR362 |
| e | TRP383 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | CYS326 |
| A | CYS329 |
| A | CYS394 |
| A | CYS397 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | LYS367 |
| A | LYS416 |
| D | LYS367 |
| D | LYS416 |
| G | LYS367 |
| G | LYS416 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | LYS367 |
| A | LYS404 |
| A | LYS416 |
| A | HOH624 |
| A | HOH626 |
| G | PRO414 |
| G | GLN415 |
| G | HOH629 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 D 501 |
| Chain | Residue |
| D | HIS381 |
| D | SER382 |
| D | TRP383 |
| D | TRP389 |
| D | TRP403 |
| D | PHE405 |
| D | HOH605 |
| M | THR362 |
| M | TRP383 |
| M | EF2501 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 502 |
| Chain | Residue |
| D | CYS326 |
| D | CYS329 |
| D | CYS394 |
| D | CYS397 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| A | PRO414 |
| A | GLN415 |
| A | HOH634 |
| D | LYS367 |
| D | LYS404 |
| D | LYS416 |
| D | HOH607 |
| D | HOH618 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 G 501 |
| Chain | Residue |
| G | HIS381 |
| G | SER382 |
| G | TRP383 |
| G | TRP389 |
| G | TRP403 |
| G | PHE405 |
| G | HOH603 |
| Y | THR362 |
| Y | TRP383 |
| Y | EF2501 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 502 |
| Chain | Residue |
| G | CYS326 |
| G | CYS329 |
| G | CYS394 |
| G | CYS397 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 G 503 |
| Chain | Residue |
| D | PRO414 |
| D | GLN415 |
| D | HOH631 |
| G | LYS367 |
| G | LYS404 |
| G | LYS416 |
| G | HOH617 |
| G | HOH626 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 J 501 |
| Chain | Residue |
| J | HIS381 |
| J | SER382 |
| J | TRP383 |
| J | TRP389 |
| J | TRP403 |
| J | PHE405 |
| J | HOH621 |
| b | THR362 |
| b | TRP383 |
| b | EF2501 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN J 502 |
| Chain | Residue |
| J | CYS326 |
| J | CYS329 |
| J | CYS394 |
| J | CYS397 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 J 503 |
| Chain | Residue |
| J | LYS367 |
| J | LYS416 |
| M | LYS367 |
| M | LYS416 |
| P | LYS367 |
| P | LYS416 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 J 504 |
| Chain | Residue |
| P | LYS416 |
| P | TRP418 |
| J | PRO414 |
| J | GLN415 |
| J | HOH626 |
| J | HOH632 |
| J | HOH636 |
| P | LYS367 |
| P | LYS404 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 J 505 |
| Chain | Residue |
| J | HIS381 |
| J | HOH607 |
| b | HIS381 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 M 501 |
| Chain | Residue |
| D | THR362 |
| D | TRP383 |
| D | EF2501 |
| M | HIS381 |
| M | SER382 |
| M | TRP383 |
| M | TRP389 |
| M | TRP403 |
| M | PHE405 |
| M | HOH606 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN M 502 |
| Chain | Residue |
| M | CYS326 |
| M | CYS329 |
| M | CYS394 |
| M | CYS397 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 M 503 |
| Chain | Residue |
| J | LYS367 |
| J | LYS404 |
| J | LYS416 |
| J | HOH611 |
| J | HOH641 |
| M | PRO414 |
| M | GLN415 |
| M | LYS416 |
| M | HOH635 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 M 504 |
| Chain | Residue |
| D | HIS381 |
| M | HIS381 |
| M | HOH601 |
| site_id | AE2 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 P 501 |
| Chain | Residue |
| P | HIS381 |
| P | SER382 |
| P | TRP383 |
| P | TRP389 |
| P | TRP403 |
| P | PHE405 |
| P | HOH625 |
| V | THR362 |
| V | TRP383 |
| V | EF2501 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN P 502 |
| Chain | Residue |
| P | CYS326 |
| P | CYS329 |
| P | CYS394 |
| P | CYS397 |
| site_id | AE4 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 P 503 |
| Chain | Residue |
| M | LYS367 |
| M | LYS404 |
| M | LYS416 |
| M | TRP418 |
| M | HOH605 |
| M | HOH631 |
| M | HOH634 |
| P | PRO414 |
| P | GLN415 |
| P | HOH640 |
| site_id | AE5 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 S 501 |
| Chain | Residue |
| S | HIS381 |
| S | SER382 |
| S | TRP383 |
| S | TRP389 |
| S | TRP403 |
| S | PHE405 |
| S | HOH618 |
| h | THR362 |
| h | TRP383 |
| h | EF2501 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN S 502 |
| Chain | Residue |
| S | CYS326 |
| S | CYS329 |
| S | CYS394 |
| S | CYS397 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 S 503 |
| Chain | Residue |
| S | LYS367 |
| S | LYS404 |
| S | LYS416 |
| S | TRP418 |
| S | HOH608 |
| S | HOH633 |
| V | PRO414 |
| V | GLN415 |
| V | HOH637 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 S 504 |
| Chain | Residue |
| S | HIS381 |
| S | HOH605 |
| h | HIS381 |
| site_id | AE9 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 V 501 |
| Chain | Residue |
| P | THR362 |
| P | TRP383 |
| P | EF2501 |
| V | HIS381 |
| V | SER382 |
| V | TRP383 |
| V | TRP389 |
| V | TRP403 |
| V | PHE405 |
| V | HOH620 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN V 502 |
| Chain | Residue |
| V | CYS326 |
| V | CYS329 |
| V | CYS394 |
| V | CYS397 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 V 503 |
| Chain | Residue |
| V | LYS367 |
| V | LYS404 |
| V | LYS416 |
| V | HOH619 |
| V | HOH634 |
| Y | PRO414 |
| Y | GLN415 |
| Y | LYS416 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 V 504 |
| Chain | Residue |
| S | LYS367 |
| S | LYS416 |
| V | LYS367 |
| V | LYS416 |
| Y | LYS367 |
| Y | LYS416 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 V 505 |
| Chain | Residue |
| P | HIS381 |
| V | HIS381 |
| V | HOH601 |
| site_id | AF5 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 Y 501 |
| Chain | Residue |
| G | THR362 |
| G | TRP383 |
| G | EF2501 |
| Y | HIS381 |
| Y | SER382 |
| Y | TRP383 |
| Y | TRP389 |
| Y | TRP403 |
| Y | PHE405 |
| Y | HOH645 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN Y 502 |
| Chain | Residue |
| Y | CYS326 |
| Y | CYS329 |
| Y | CYS394 |
| Y | CYS397 |
| site_id | AF7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 Y 503 |
| Chain | Residue |
| S | PRO414 |
| S | GLN415 |
| Y | LYS367 |
| Y | LYS404 |
| Y | LYS416 |
| Y | TRP418 |
| Y | HOH608 |
| Y | HOH630 |
| Y | HOH633 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 Y 504 |
| Chain | Residue |
| G | HIS381 |
| Y | HIS381 |
| Y | HOH601 |
| site_id | AF9 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 b 501 |
| Chain | Residue |
| J | THR362 |
| J | TRP383 |
| J | EF2501 |
| b | HIS381 |
| b | SER382 |
| b | TRP383 |
| b | TRP389 |
| b | TRP403 |
| b | PHE405 |
| b | HOH620 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN b 502 |
| Chain | Residue |
| b | CYS326 |
| b | CYS329 |
| b | CYS394 |
| b | CYS397 |
| site_id | AG2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 b 503 |
| Chain | Residue |
| b | LYS367 |
| b | LYS404 |
| b | LYS416 |
| b | TRP418 |
| b | HOH605 |
| b | HOH632 |
| h | PRO414 |
| h | GLN415 |
| h | HOH632 |
| site_id | AG3 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 e 501 |
| Chain | Residue |
| A | THR362 |
| A | TRP383 |
| A | EF2501 |
| e | HIS381 |
| e | SER382 |
| e | TRP383 |
| e | TRP389 |
| e | TRP403 |
| e | PHE405 |
| e | HOH633 |
| site_id | AG4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN e 502 |
| Chain | Residue |
| e | CYS326 |
| e | CYS329 |
| e | CYS394 |
| e | CYS397 |
| site_id | AG5 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 e 503 |
| Chain | Residue |
| b | PRO414 |
| b | GLN415 |
| e | LYS367 |
| e | LYS404 |
| e | LYS416 |
| e | TRP418 |
| e | HOH605 |
| e | HOH620 |
| e | HOH630 |
| e | HOH634 |
| site_id | AG6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 e 504 |
| Chain | Residue |
| e | PRO414 |
| e | GLN415 |
| e | LYS416 |
| e | HOH626 |
| e | HOH629 |
| h | LYS367 |
| h | LYS404 |
| h | LYS416 |
| h | HOH641 |
| site_id | AG7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 e 505 |
| Chain | Residue |
| A | HIS381 |
| e | HIS381 |
| e | HOH602 |
| site_id | AG8 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 h 501 |
| Chain | Residue |
| S | THR362 |
| S | TRP383 |
| S | EF2501 |
| h | HIS381 |
| h | SER382 |
| h | TRP383 |
| h | TRP389 |
| h | TRP403 |
| h | PHE405 |
| h | HOH615 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN h 502 |
| Chain | Residue |
| h | CYS326 |
| h | CYS329 |
| h | CYS394 |
| h | CYS397 |
| site_id | AH1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 h 503 |
| Chain | Residue |
| b | LYS367 |
| b | LYS416 |
| e | LYS367 |
| e | LYS416 |
| h | LYS367 |
| h | LYS416 |
| site_id | AH2 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 k 501 |
| Chain | Residue |
| k | HIS381 |
| k | SER382 |
| k | TRP383 |
| k | TRP389 |
| k | TRP403 |
| k | PHE405 |
| k | HOH642 |
| t | THR362 |
| t | TRP383 |
| t | EF2501 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN k 502 |
| Chain | Residue |
| k | CYS326 |
| k | CYS329 |
| k | CYS394 |
| k | CYS397 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 k 503 |
| Chain | Residue |
| k | HIS381 |
| k | HOH602 |
| t | HIS381 |
| site_id | AH5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 k 504 |
| Chain | Residue |
| k | PRO414 |
| k | GLN415 |
| k | LYS416 |
| n | LYS367 |
| n | LYS416 |
| n | HOH642 |
| site_id | AH6 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 n 501 |
| Chain | Residue |
| n | HIS381 |
| n | SER382 |
| n | TRP383 |
| n | TRP389 |
| n | TRP403 |
| n | PHE405 |
| n | HOH615 |
| q | THR362 |
| q | TRP383 |
| q | EF2501 |
| site_id | AH7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN n 502 |
| Chain | Residue |
| n | CYS326 |
| n | CYS329 |
| n | CYS394 |
| n | CYS397 |
| site_id | AH8 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 n 503 |
| Chain | Residue |
| n | PRO414 |
| n | GLN415 |
| n | HOH622 |
| n | HOH625 |
| n | HOH634 |
| q | LYS367 |
| q | LYS404 |
| q | LYS416 |
| q | TRP418 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 n 504 |
| Chain | Residue |
| k | LYS367 |
| k | LYS416 |
| n | LYS367 |
| n | LYS416 |
| q | LYS367 |
| q | LYS416 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 n 505 |
| Chain | Residue |
| n | HIS381 |
| n | HOH603 |
| q | HIS381 |
| site_id | AI2 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 q 501 |
| Chain | Residue |
| n | THR362 |
| n | TRP383 |
| n | EF2501 |
| q | HIS381 |
| q | SER382 |
| q | TRP383 |
| q | TRP389 |
| q | TRP403 |
| q | PHE405 |
| q | HOH603 |
| site_id | AI3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN q 502 |
| Chain | Residue |
| q | CYS326 |
| q | CYS329 |
| q | CYS394 |
| q | CYS397 |
| site_id | AI4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 q 503 |
| Chain | Residue |
| k | LYS367 |
| k | LYS404 |
| k | LYS416 |
| k | TRP418 |
| k | HOH605 |
| k | HOH629 |
| q | PRO414 |
| q | GLN415 |
| q | HOH631 |
| site_id | AI5 |
| Number of Residues | 10 |
| Details | binding site for residue EF2 t 501 |
| Chain | Residue |
| k | THR362 |
| k | TRP383 |
| k | EF2501 |
| t | HIS381 |
| t | SER382 |
| t | TRP383 |
| t | TRP389 |
| t | TRP403 |
| t | PHE405 |
| t | HOH603 |
| site_id | AI6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN t 502 |
| Chain | Residue |
| t | CYS326 |
| t | CYS329 |
| t | CYS394 |
| t | CYS397 |
| site_id | AI7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 t 503 |
| Chain | Residue |
| t | LYS367 |
| t | LYS404 |
| t | PRO414 |
| t | GLN415 |
| t | LYS416 |
| t | HOH608 |
| t | HOH622 |
| t | HOH624 |
| t | HOH629 |
| site_id | AI8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 t 504 |
| Chain | Residue |
| t | LYS367 |
| t | LYS367 |
| t | LYS367 |
| t | LYS416 |
| t | LYS416 |
| t | LYS416 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25108355","evidenceCode":"ECO:0000269"}]} |
