5YH3
The structure of hFam20C and hFam20A complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001934 | biological_process | positive regulation of protein phosphorylation |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0031214 | biological_process | biomineral tissue development |
| A | 0043539 | molecular_function | protein serine/threonine kinase activator activity |
| A | 0044691 | biological_process | tooth eruption |
| A | 0055074 | biological_process | calcium ion homeostasis |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070166 | biological_process | enamel mineralization |
| B | 0001934 | biological_process | positive regulation of protein phosphorylation |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0031214 | biological_process | biomineral tissue development |
| B | 0043539 | molecular_function | protein serine/threonine kinase activator activity |
| B | 0044691 | biological_process | tooth eruption |
| B | 0055074 | biological_process | calcium ion homeostasis |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0070166 | biological_process | enamel mineralization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue ATP A 701 |
| Chain | Residue |
| A | TYR125 |
| A | SER346 |
| A | LEU347 |
| A | ARG352 |
| A | LEU429 |
| A | ASP430 |
| C | LYS347 |
| A | LYS129 |
| A | LYS233 |
| A | MET235 |
| A | PRO279 |
| A | SER341 |
| A | ALA342 |
| A | PHE343 |
| A | LEU344 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue ATP A 702 |
| Chain | Residue |
| A | LYS129 |
| A | ARG132 |
| A | ARG136 |
| A | TYR140 |
| A | GLN143 |
| A | SER195 |
| A | ASP197 |
| A | LYS203 |
| A | LYS297 |
| A | ASN298 |
| A | GLU299 |
| C | LYS347 |
| C | ARG351 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue ATP B 701 |
| Chain | Residue |
| B | TYR125 |
| B | LYS129 |
| B | LYS233 |
| B | MET235 |
| B | PRO279 |
| B | SER341 |
| B | ALA342 |
| B | LEU344 |
| B | SER346 |
| B | LEU347 |
| B | ARG352 |
| B | ATP702 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue ATP B 702 |
| Chain | Residue |
| B | LYS129 |
| B | ARG132 |
| B | ARG136 |
| B | TYR140 |
| B | GLN143 |
| B | SER195 |
| B | ASP197 |
| B | LYS203 |
| B | ARG227 |
| B | LYS297 |
| B | ATP701 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 211 |
| Details | Region: {"description":"Kinase domain","evidences":[{"source":"PubMed","id":"22582013","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"23754375","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9XTW2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22582013","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"26091039","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26091039","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
