5YEV
Murine DR3 death domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0006974 | biological_process | DNA damage response |
| A | 0007165 | biological_process | signal transduction |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0015768 | biological_process | maltose transport |
| A | 0016020 | cellular_component | membrane |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 0034289 | biological_process | detection of maltose stimulus |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0042956 | biological_process | maltodextrin transmembrane transport |
| A | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| A | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0060326 | biological_process | cell chemotaxis |
| A | 1901982 | molecular_function | maltose binding |
| A | 1990060 | cellular_component | maltose transport complex |
| B | 0005515 | molecular_function | protein binding |
| B | 0006974 | biological_process | DNA damage response |
| B | 0007165 | biological_process | signal transduction |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0015768 | biological_process | maltose transport |
| B | 0016020 | cellular_component | membrane |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0034219 | biological_process | carbohydrate transmembrane transport |
| B | 0034289 | biological_process | detection of maltose stimulus |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0042956 | biological_process | maltodextrin transmembrane transport |
| B | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| B | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0060326 | biological_process | cell chemotaxis |
| B | 1901982 | molecular_function | maltose binding |
| B | 1990060 | cellular_component | maltose transport complex |
| C | 0005515 | molecular_function | protein binding |
| C | 0006974 | biological_process | DNA damage response |
| C | 0007165 | biological_process | signal transduction |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0015768 | biological_process | maltose transport |
| C | 0016020 | cellular_component | membrane |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0034219 | biological_process | carbohydrate transmembrane transport |
| C | 0034289 | biological_process | detection of maltose stimulus |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0042956 | biological_process | maltodextrin transmembrane transport |
| C | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| C | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| C | 0055085 | biological_process | transmembrane transport |
| C | 0060326 | biological_process | cell chemotaxis |
| C | 1901982 | molecular_function | maltose binding |
| C | 1990060 | cellular_component | maltose transport complex |
| D | 0005515 | molecular_function | protein binding |
| D | 0006974 | biological_process | DNA damage response |
| D | 0007165 | biological_process | signal transduction |
| D | 0008643 | biological_process | carbohydrate transport |
| D | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| D | 0015768 | biological_process | maltose transport |
| D | 0016020 | cellular_component | membrane |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0034219 | biological_process | carbohydrate transmembrane transport |
| D | 0034289 | biological_process | detection of maltose stimulus |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0042956 | biological_process | maltodextrin transmembrane transport |
| D | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| D | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| D | 0055085 | biological_process | transmembrane transport |
| D | 0060326 | biological_process | cell chemotaxis |
| D | 1901982 | molecular_function | maltose binding |
| D | 1990060 | cellular_component | maltose transport complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ARG411 |
| B | ARG413 |
| C | ARG411 |
| D | TRP388 |
| D | ARG413 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | GLY432 |
| A | ALA433 |
| A | ILE434 |
| A | ARG424 |
| A | ALA429 |
| A | GLY430 |
| A | LEU431 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | ARG371 |
| A | ALA372 |
| A | ALA373 |
| B | LYS421 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | ASN151 |
| A | GLU154 |
| A | ASP210 |
| A | TYR211 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ASN186 |
| A | ALA187 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| B | ARG411 |
| B | PHE412 |
| C | ARG411 |
| C | PHE412 |
| C | ARG413 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | ARG424 |
| B | GLY430 |
| B | LEU431 |
| B | GLY432 |
| B | ALA433 |
| B | ILE434 |
| B | HOH601 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| A | LYS421 |
| B | ARG371 |
| B | ALA372 |
| B | ALA373 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | ALA78 |
| B | GLU79 |
| B | LYS274 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | ASN186 |
| B | ALA187 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 501 |
| Chain | Residue |
| C | ARG424 |
| C | GLY430 |
| C | LEU431 |
| C | GLY432 |
| C | ALA433 |
| C | ILE434 |
| C | HOH606 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| A | LYS190 |
| C | HOH612 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 503 |
| Chain | Residue |
| C | ASN151 |
| C | GLN153 |
| C | ASP210 |
| C | TYR211 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 504 |
| Chain | Residue |
| C | ASN186 |
| C | ALA187 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 501 |
| Chain | Residue |
| A | ARG413 |
| B | ARG411 |
| C | ALA385 |
| C | TRP388 |
| C | ARG413 |
| D | ARG411 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 502 |
| Chain | Residue |
| A | ARG411 |
| A | PHE412 |
| D | ARG411 |
| D | PHE412 |
| D | ARG413 |
| D | HOH608 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| D | TRP423 |
| D | ARG424 |
| D | ALA429 |
| D | GLY430 |
| D | LEU431 |
| D | GLY432 |
| D | ALA433 |
| D | ILE434 |
| D | HOH602 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 504 |
| Chain | Residue |
| B | LYS190 |
| D | PRO134 |
| D | HOH601 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 505 |
| Chain | Residue |
| B | LYS89 |
| D | LYS171 |
| D | TYR172 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 506 |
| Chain | Residue |
| C | GLU418 |
| C | LYS421 |
| D | ARG371 |
| D | ALA372 |
| D | ALA373 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 507 |
| Chain | Residue |
| D | ASN151 |
| D | ASP210 |
| D | TYR211 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 508 |
| Chain | Residue |
| C | ARG371 |
| C | ALA373 |
| D | LYS421 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 509 |
| Chain | Residue |
| D | ASN186 |
| D | ALA187 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 510 |
| Chain | Residue |
| D | ASP42 |
| D | LYS47 |
| D | PRO41 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 511 |
| Chain | Residue |
| D | LYS389 |
| D | ARG393 |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| A | PRO108-ASN125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000305|PubMed:30979585 |
| Chain | Residue | Details |
| A | ARG393 | |
| B | ARG393 | |
| C | ARG393 | |
| D | ARG393 |
