Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5YEV

Murine DR3 death domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006974	biological_process	DNA damage response
A	0007165	biological_process	signal transduction
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0005515	molecular_function	protein binding
B	0006974	biological_process	DNA damage response
B	0007165	biological_process	signal transduction
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex
C	0005515	molecular_function	protein binding
C	0006974	biological_process	DNA damage response
C	0007165	biological_process	signal transduction
C	0008643	biological_process	carbohydrate transport
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex
D	0005515	molecular_function	protein binding
D	0006974	biological_process	DNA damage response
D	0007165	biological_process	signal transduction
D	0008643	biological_process	carbohydrate transport
D	0015144	molecular_function	carbohydrate transmembrane transporter activity
D	0015768	biological_process	maltose transport
D	0016020	cellular_component	membrane
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0034219	biological_process	carbohydrate transmembrane transport
D	0034289	biological_process	detection of maltose stimulus
D	0042597	cellular_component	periplasmic space
D	0042956	biological_process	maltodextrin transmembrane transport
D	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	0055085	biological_process	transmembrane transport
D	0060326	biological_process	cell chemotaxis
D	1901982	molecular_function	maltose binding
D	1990060	cellular_component	maltose transport complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 501

Chain	Residue
A	ARG411
B	ARG413
C	ARG411
D	TRP388
D	ARG413

site_id	AC2
Number of Residues	7
Details	binding site for residue SO4 A 502

Chain	Residue
A	GLY432
A	ALA433
A	ILE434
A	ARG424
A	ALA429
A	GLY430
A	LEU431

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 503

Chain	Residue
A	ARG371
A	ALA372
A	ALA373
B	LYS421

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 504

Chain	Residue
A	ASN151
A	GLU154
A	ASP210
A	TYR211

site_id	AC5
Number of Residues	2
Details	binding site for residue SO4 A 505

Chain	Residue
A	ASN186
A	ALA187

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 B 501

Chain	Residue
B	ARG411
B	PHE412
C	ARG411
C	PHE412
C	ARG413

site_id	AC7
Number of Residues	7
Details	binding site for residue SO4 B 502

Chain	Residue
B	ARG424
B	GLY430
B	LEU431
B	GLY432
B	ALA433
B	ILE434
B	HOH601

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 B 503

Chain	Residue
A	LYS421
B	ARG371
B	ALA372
B	ALA373

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 B 504

Chain	Residue
B	ALA78
B	GLU79
B	LYS274

site_id	AD1
Number of Residues	2
Details	binding site for residue SO4 B 505

Chain	Residue
B	ASN186
B	ALA187

site_id	AD2
Number of Residues	7
Details	binding site for residue SO4 C 501

Chain	Residue
C	ARG424
C	GLY430
C	LEU431
C	GLY432
C	ALA433
C	ILE434
C	HOH606

site_id	AD3
Number of Residues	2
Details	binding site for residue SO4 C 502

Chain	Residue
A	LYS190
C	HOH612

site_id	AD4
Number of Residues	4
Details	binding site for residue SO4 C 503

Chain	Residue
C	ASN151
C	GLN153
C	ASP210
C	TYR211

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 C 504

Chain	Residue
C	ASN186
C	ALA187

site_id	AD6
Number of Residues	6
Details	binding site for residue SO4 D 501

Chain	Residue
A	ARG413
B	ARG411
C	ALA385
C	TRP388
C	ARG413
D	ARG411

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 D 502

Chain	Residue
A	ARG411
A	PHE412
D	ARG411
D	PHE412
D	ARG413
D	HOH608

site_id	AD8
Number of Residues	9
Details	binding site for residue SO4 D 503

Chain	Residue
D	TRP423
D	ARG424
D	ALA429
D	GLY430
D	LEU431
D	GLY432
D	ALA433
D	ILE434
D	HOH602

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 D 504

Chain	Residue
B	LYS190
D	PRO134
D	HOH601

site_id	AE1
Number of Residues	3
Details	binding site for residue SO4 D 505

Chain	Residue
B	LYS89
D	LYS171
D	TYR172

site_id	AE2
Number of Residues	5
Details	binding site for residue SO4 D 506

Chain	Residue
C	GLU418
C	LYS421
D	ARG371
D	ALA372
D	ALA373

site_id	AE3
Number of Residues	3
Details	binding site for residue SO4 D 507

Chain	Residue
D	ASN151
D	ASP210
D	TYR211

site_id	AE4
Number of Residues	3
Details	binding site for residue SO4 D 508

Chain	Residue
C	ARG371
C	ALA373
D	LYS421

site_id	AE5
Number of Residues	2
Details	binding site for residue SO4 D 509

Chain	Residue
D	ASN186
D	ALA187

site_id	AE6
Number of Residues	3
Details	binding site for residue SO4 D 510

Chain	Residue
D	ASP42
D	LYS47
D	PRO41

site_id	AE7
Number of Residues	2
Details	binding site for residue SO4 D 511

Chain	Residue
D	LYS389
D	ARG393

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO108-ASN125

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	324
Details	Domain: {"description":"Death","evidences":[{"source":"PROSITE-ProRule","id":"PRU00064","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"(Microbial infection) N-beta-linked (GlcNAc) arginine","evidences":[{"source":"PubMed","id":"30979585","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)