5XMY

Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1001

Chain	Residue
A	CYS885
A	CYS888
A	CYS911
A	CYS914

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1002

Chain	Residue
A	CYS870
A	CYS873
A	HIS893
A	CYS896

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN C 1001

Chain	Residue
C	CYS888
C	CYS911
C	CYS914
C	CYS885

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN C 1002

Chain	Residue
C	CYS870
C	CYS873
C	HIS893
C	CYS896

---

site_id	AC5
Number of Residues	9
Details	binding site for Ligand residues M3L D 4 through GLN D 5 bound to THR D 3

Chain	Residue
A	TRP863
C	TRP868
C	ASP877
C	GLY879
C	PRO881
C	MET882
C	TRP891
D	THR3
D	THR6

---

site_id	AC6
Number of Residues	11
Details	binding site for Ligand residues M3L P 4 through GLN P 5 bound to THR P 3

Chain	Residue
A	TRP868
A	ASP877
A	GLY879
A	PRO881
A	MET882
A	TRP891
C	TRP863
P	THR3
P	THR6
P	HOH102
P	HOH104

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	45
Details	ZF_PHD_1 Zinc finger PHD-type signature. CpgCnkpddgspm....................................IgCdd..Cddw.YHwpCvgimtappeemq.................................WfCpkC

Chain	Residue	Details
A	CYS870-CYS914

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	ZN_FING: PHD-type => ECO:0000255|PROSITE-ProRule:PRU00146

Chain	Residue	Details
A	ILE867-LYS917
C	ILE867-LYS917

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0007744|PDB:5C13

Chain	Residue	Details
A	CYS870
C	CYS873
C	CYS885
C	CYS888
C	HIS893
C	CYS896
C	CYS911
C	CYS914
A	CYS873
A	CYS885
A	CYS888
A	HIS893
A	CYS896
A	CYS911
A	CYS914
C	CYS870

---