5XKO
Crystal structure of native Msmeg3575 deaminase from Mycobacterium smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004131 | molecular_function | cytosine deaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008655 | biological_process | pyrimidine-containing compound salvage |
| A | 0019858 | biological_process | cytosine metabolic process |
| A | 0046087 | biological_process | cytidine metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004131 | molecular_function | cytosine deaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008655 | biological_process | pyrimidine-containing compound salvage |
| B | 0019858 | biological_process | cytosine metabolic process |
| B | 0046087 | biological_process | cytidine metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue CAC A 201 |
| Chain | Residue |
| A | PHE29 |
| A | ZN203 |
| A | HOH372 |
| A | HIS56 |
| A | PRO57 |
| A | GLU58 |
| A | GLY83 |
| A | GLU84 |
| A | CYS86 |
| A | CYS89 |
| A | GOL202 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | GLU27 |
| A | CAC201 |
| A | HOH308 |
| A | HOH361 |
| A | HOH415 |
| B | TRP95 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 203 |
| Chain | Residue |
| A | HIS56 |
| A | CYS86 |
| A | CYS89 |
| A | CAC201 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue CAC B 201 |
| Chain | Residue |
| B | PHE29 |
| B | HIS56 |
| B | GLU58 |
| B | GLY83 |
| B | GLU84 |
| B | CYS86 |
| B | CYS89 |
| B | ZN202 |
| B | GOL204 |
| B | HOH356 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 202 |
| Chain | Residue |
| B | HIS56 |
| B | CYS86 |
| B | CYS89 |
| B | CAC201 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| A | ASN151 |
| B | ARG12 |
| B | ARG19 |
| B | LEU145 |
| B | THR148 |
| B | GOL205 |
| B | HOH306 |
| B | HOH311 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 204 |
| Chain | Residue |
| A | TRP95 |
| B | GLU27 |
| B | PHE29 |
| B | PRO122 |
| B | PHE157 |
| B | CAC201 |
| B | HOH318 |
| B | HOH370 |
| B | HOH377 |
| B | HOH393 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 205 |
| Chain | Residue |
| A | ARG19 |
| A | LEU152 |
| B | ASN151 |
| B | GOL203 |
| B | ACT207 |
| B | HOH302 |
| B | HOH303 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 206 |
| Chain | Residue |
| B | TRP117 |
| B | GLY118 |
| B | ARG159 |
| B | HOH335 |
| B | HOH346 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 207 |
| Chain | Residue |
| A | ASN151 |
| A | ARG154 |
| A | ALA155 |
| B | ARG19 |
| B | THR148 |
| B | GOL205 |
