5XIL

Crystal Structure of Leishmania major Prolyl-tRNA Synthetase (LmPRS)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004827	molecular_function	proline-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006433	biological_process	prolyl-tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1001

Chain	Residue
A	CYS687
A	CYS692
A	CYS737
A	ACT1002

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site_id	AC2
Number of Residues	7
Details	binding site for residue ACT A 1002

Chain	Residue
A	LYS744
A	ZN1001
A	CYS687
A	CYS692
A	CYS737
A	CYS742
A	THR743

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site_id	AC3
Number of Residues	7
Details	binding site for residue ACT A 1003

Chain	Residue
A	PHE263
A	SER264
A	TYR267
A	MET523
A	TYR756
A	HOH1157
A	HOH1257

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site_id	AC4
Number of Residues	4
Details	binding site for residue ACT A 1004

Chain	Residue
A	ARG665
A	THR667
A	GLU730
A	GLU730

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site_id	AC5
Number of Residues	6
Details	binding site for residue MG A 1005

Chain	Residue
A	GLU468
A	HIS662
A	HOH1172
A	HOH1199
A	HOH1217
A	HOH1297

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site_id	AC6
Number of Residues	7
Details	binding site for residue MG A 1006

Chain	Residue
A	LYS453
A	HOH1101
A	HOH1158
A	HOH1324
A	HOH1343
A	HOH1409
A	HOH1455

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site_id	AC7
Number of Residues	5
Details	binding site for residue MG A 1007

Chain	Residue
A	GLU736
A	HOH1192
A	HOH1228
A	HOH1275
A	HOH1319

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