5WTJ

Crystal structure of an endonuclease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0051607	biological_process	defense response to virus
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0051607	biological_process	defense response to virus

Functional Information from PROSITE/UniProt

site_id	PS00268
Number of Residues	9
Details	CECROPIN Cecropin family signature. W..NITKRIEK

Chain	Residue	Details
A	TRP305-LYS313

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Region: {"description":"Binds crRNA","evidences":[{"source":"PubMed","id":"28086085","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	60
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"For pre-crRNA processing","evidences":[{"source":"PubMed","id":"28086085","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Active site: {"description":"For target ssRNA cleavage","evidences":[{"source":"PubMed","id":"27256883","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28086085","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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