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5WT2

NifS from Helicobacter pylori

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006534biological_processcysteine metabolic process
A0016226biological_processiron-sulfur cluster assembly
A0016740molecular_functiontransferase activity
A0030170molecular_functionpyridoxal phosphate binding
A0031071molecular_functioncysteine desulfurase activity
A0044571biological_process[2Fe-2S] cluster assembly
A0046872molecular_functionmetal ion binding
A0051537molecular_function2 iron, 2 sulfur cluster binding
Functional Information from PDB Data
site_idAC1
Number of Residues13
Detailsbinding site for residue PLP A 501
ChainResidue
ACYS72
ALYS206
AGLY240
ATHR241
AHOH640
AALA73
ATHR74
AHIS104
AASP180
AVAL182
AGLN183
ASER203
AHIS205

site_idAC2
Number of Residues6
Detailsbinding site for residue IPA A 502
ChainResidue
ALEU52
ATYR56
AASP66
AVAL67
AILE68
AASN235

site_idAC3
Number of Residues2
Detailsbinding site for residue CL A 503
ChainResidue
ALYS82
APRO226

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Cysteine persulfide intermediate => ECO:0000255|HAMAP-Rule:MF_00331
ChainResidueDetails
ACYS328

site_idSWS_FT_FI2
Number of Residues5
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00331
ChainResidueDetails
AALA73
AASN155
AGLN183
ASER203
ATHR241

site_idSWS_FT_FI3
Number of Residues1
DetailsBINDING: via persulfide group => ECO:0000255|HAMAP-Rule:MF_00331
ChainResidueDetails
ACYS328

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_00331
ChainResidueDetails
ALYS206

226707

PDB entries from 2024-10-30

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