Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5WMH

Arabidopsis thaliana prephenate aminotransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
A	0005829	cellular_component	cytosol
A	0008483	molecular_function	transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009094	biological_process	L-phenylalanine biosynthetic process
A	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
A	0009507	cellular_component	chloroplast
A	0009536	cellular_component	plastid
A	0009570	cellular_component	chloroplast stroma
A	0009793	biological_process	embryo development ending in seed dormancy
A	0016740	molecular_function	transferase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0033853	molecular_function	aspartate-prephenate aminotransferase activity
A	0033854	molecular_function	glutamate-prephenate aminotransferase activity
B	0003824	molecular_function	catalytic activity
B	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
B	0005829	cellular_component	cytosol
B	0008483	molecular_function	transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0009094	biological_process	L-phenylalanine biosynthetic process
B	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
B	0009507	cellular_component	chloroplast
B	0009536	cellular_component	plastid
B	0009570	cellular_component	chloroplast stroma
B	0009793	biological_process	embryo development ending in seed dormancy
B	0016740	molecular_function	transferase activity
B	0030170	molecular_function	pyridoxal phosphate binding
B	0033853	molecular_function	aspartate-prephenate aminotransferase activity
B	0033854	molecular_function	glutamate-prephenate aminotransferase activity
C	0003824	molecular_function	catalytic activity
C	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
C	0005829	cellular_component	cytosol
C	0008483	molecular_function	transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0009094	biological_process	L-phenylalanine biosynthetic process
C	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
C	0009507	cellular_component	chloroplast
C	0009536	cellular_component	plastid
C	0009570	cellular_component	chloroplast stroma
C	0009793	biological_process	embryo development ending in seed dormancy
C	0016740	molecular_function	transferase activity
C	0030170	molecular_function	pyridoxal phosphate binding
C	0033853	molecular_function	aspartate-prephenate aminotransferase activity
C	0033854	molecular_function	glutamate-prephenate aminotransferase activity
D	0003824	molecular_function	catalytic activity
D	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
D	0005829	cellular_component	cytosol
D	0008483	molecular_function	transaminase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0009094	biological_process	L-phenylalanine biosynthetic process
D	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
D	0009507	cellular_component	chloroplast
D	0009536	cellular_component	plastid
D	0009570	cellular_component	chloroplast stroma
D	0009793	biological_process	embryo development ending in seed dormancy
D	0016740	molecular_function	transferase activity
D	0030170	molecular_function	pyridoxal phosphate binding
D	0033853	molecular_function	aspartate-prephenate aminotransferase activity
D	0033854	molecular_function	glutamate-prephenate aminotransferase activity
E	0003824	molecular_function	catalytic activity
E	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
E	0005829	cellular_component	cytosol
E	0008483	molecular_function	transaminase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009058	biological_process	biosynthetic process
E	0009094	biological_process	L-phenylalanine biosynthetic process
E	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
E	0009507	cellular_component	chloroplast
E	0009536	cellular_component	plastid
E	0009570	cellular_component	chloroplast stroma
E	0009793	biological_process	embryo development ending in seed dormancy
E	0016740	molecular_function	transferase activity
E	0030170	molecular_function	pyridoxal phosphate binding
E	0033853	molecular_function	aspartate-prephenate aminotransferase activity
E	0033854	molecular_function	glutamate-prephenate aminotransferase activity
F	0003824	molecular_function	catalytic activity
F	0004069	molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity
F	0005829	cellular_component	cytosol
F	0008483	molecular_function	transaminase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009058	biological_process	biosynthetic process
F	0009094	biological_process	L-phenylalanine biosynthetic process
F	0009095	biological_process	aromatic amino acid family biosynthetic process, prephenate pathway
F	0009507	cellular_component	chloroplast
F	0009536	cellular_component	plastid
F	0009570	cellular_component	chloroplast stroma
F	0009793	biological_process	embryo development ending in seed dormancy
F	0016740	molecular_function	transferase activity
F	0030170	molecular_function	pyridoxal phosphate binding
F	0033853	molecular_function	aspartate-prephenate aminotransferase activity
F	0033854	molecular_function	glutamate-prephenate aminotransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue PLP A 701

Chain	Residue
A	GLY167
A	LYS306
A	ARG314
B	TYR132
A	ALA168
A	LYS169
A	TRP193
A	ASN243
A	ASP272
A	ILE274
A	TYR275
A	SER305

site_id	AC2
Number of Residues	13
Details	binding site for residue PLP B 701

Chain	Residue
A	TYR132
B	GLY167
B	ALA168
B	LYS169
B	TRP193
B	CYS239
B	ASN243
B	ASP272
B	ILE274
B	TYR275
B	SER305
B	LYS306
B	ARG314

site_id	AC3
Number of Residues	12
Details	binding site for residue PLP C 701

Chain	Residue
C	GLY167
C	ALA168
C	LYS169
C	TRP193
C	ASN243
C	ASP272
C	ILE274
C	TYR275
C	SER305
C	LYS306
C	ARG314
D	TYR132

site_id	AC4
Number of Residues	13
Details	binding site for residue PLP D 701

Chain	Residue
C	TYR132
D	GLY167
D	ALA168
D	LYS169
D	TRP193
D	CYS239
D	ASN243
D	ASP272
D	ILE274
D	TYR275
D	SER305
D	LYS306
D	ARG314

site_id	AC5
Number of Residues	11
Details	binding site for residue PLP E 701

Chain	Residue
E	GLY167
E	ALA168
E	LYS169
E	TRP193
E	ASN243
E	ASP272
E	TYR275
E	SER305
E	LYS306
E	ARG314
F	TYR132

site_id	AC6
Number of Residues	10
Details	binding site for residue PLP F 701

Chain	Residue
E	TYR132
F	GLY167
F	ALA168
F	LYS169
F	TRP193
F	ASP272
F	ILE274
F	TYR275
F	SER305
F	LYS306

Functional Information from PROSITE/UniProt

site_id	PS00105
Number of Residues	14
Details	AA_TRANSFER_CLASS_1 Aminotransferases class-I pyridoxal-phosphate attachment site. GFSKafAMtGWRLG

Chain	Residue	Details
A	GLY303-GLY316

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY107
C	TRP193
C	ASN243
C	ARG445
D	GLY107
D	TRP193
D	ASN243
D	ARG445
E	GLY107
E	TRP193
E	ASN243
A	TRP193
E	ARG445
F	GLY107
F	TRP193
F	ASN243
F	ARG445
A	ASN243
A	ARG445
B	GLY107
B	TRP193
B	ASN243
B	ARG445
C	GLY107

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250

Chain	Residue	Details
A	LYS306
B	LYS306
C	LYS306
D	LYS306
E	LYS306
F	LYS306

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)