5WMF

Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006275	biological_process	regulation of DNA replication
A	0006355	biological_process	regulation of DNA-templated transcription
A	0042025	cellular_component	host cell nucleus
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006275	biological_process	regulation of DNA replication
B	0006355	biological_process	regulation of DNA-templated transcription
B	0042025	cellular_component	host cell nucleus
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006275	biological_process	regulation of DNA replication
C	0006355	biological_process	regulation of DNA-templated transcription
C	0042025	cellular_component	host cell nucleus
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006275	biological_process	regulation of DNA replication
D	0006355	biological_process	regulation of DNA-templated transcription
D	0042025	cellular_component	host cell nucleus
D	0045893	biological_process	positive regulation of DNA-templated transcription
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006275	biological_process	regulation of DNA replication
E	0006355	biological_process	regulation of DNA-templated transcription
E	0042025	cellular_component	host cell nucleus
E	0045893	biological_process	positive regulation of DNA-templated transcription
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006275	biological_process	regulation of DNA replication
F	0006355	biological_process	regulation of DNA-templated transcription
F	0042025	cellular_component	host cell nucleus
F	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"For site-specific DNA endonuclease activity","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Site: {"description":"Interaction dimer-dimer","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Site: {"description":"Interaction dimer-dimer. Required for episome maintenance and generation of immortalized B cells in the host","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---