5WLH

Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue IOD A 1501

Chain	Residue
A	ASP210
A	PRO211

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 1503

Chain	Residue
A	ARG1126

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site_id	AC3
Number of Residues	2
Details	binding site for residue IOD A 1505

Chain	Residue
A	LYS528
A	SER1201

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site_id	AC4
Number of Residues	1
Details	binding site for residue IOD A 1506

Chain	Residue
A	LYS615

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site_id	AC5
Number of Residues	1
Details	binding site for residue IOD A 1507

Chain	Residue
A	ARG40

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site_id	AC6
Number of Residues	1
Details	binding site for residue IOD A 1509

Chain	Residue
A	ASP1113

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site_id	AC7
Number of Residues	1
Details	binding site for residue IOD A 1510

Chain	Residue
A	ARG848

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site_id	AC8
Number of Residues	1
Details	binding site for residue IOD A 1511

Chain	Residue
A	LYS1052

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site_id	AC9
Number of Residues	1
Details	binding site for residue IOD A 1512

Chain	Residue
A	ASP393

---

site_id	AD1
Number of Residues	1
Details	binding site for residue IOD A 1513

Chain	Residue
A	GLN1158

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site_id	AD2
Number of Residues	2
Details	binding site for residue IOD A 1515

Chain	Residue
A	SER1191
A	ARG1211

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site_id	AD3
Number of Residues	2
Details	binding site for residue IOD A 1516

Chain	Residue
A	PHE524
A	HOH1647

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site_id	AD4
Number of Residues	1
Details	binding site for residue IOD A 1517

Chain	Residue
A	ASP1350

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site_id	AD5
Number of Residues	2
Details	binding site for residue IOD A 1518

Chain	Residue
A	TYR928
A	HOH2029

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site_id	AD6
Number of Residues	1
Details	binding site for residue IOD A 1519

Chain	Residue
A	ASP576

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site_id	AD7
Number of Residues	1
Details	binding site for residue IOD A 1520

Chain	Residue
A	LYS340

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site_id	AD8
Number of Residues	10
Details	binding site for residue GOL A 1521

Chain	Residue
A	ASN36
A	GLY42
A	LYS43
A	ARG45
A	LYS46
A	ASN47
A	ASP50
A	GLU1192
A	HOH1606
A	HOH1771

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