5WE0

Structural Basis for Shelterin Bridge Assembly

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000723	biological_process	telomere maintenance
A	0000781	cellular_component	chromosome, telomeric region
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0010833	biological_process	telomere maintenance via telomere lengthening
A	0016233	biological_process	telomere capping
A	0032200	biological_process	telomere organization
A	0032206	biological_process	positive regulation of telomere maintenance
A	0070187	cellular_component	shelterin complex
A	0140445	cellular_component	chromosome, telomeric repeat region
D	0000723	biological_process	telomere maintenance
D	0000781	cellular_component	chromosome, telomeric region
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0010833	biological_process	telomere maintenance via telomere lengthening
D	0016233	biological_process	telomere capping
D	0032200	biological_process	telomere organization
D	0032206	biological_process	positive regulation of telomere maintenance
D	0070187	cellular_component	shelterin complex
D	0140445	cellular_component	chromosome, telomeric repeat region
G	0000723	biological_process	telomere maintenance
G	0000781	cellular_component	chromosome, telomeric region
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0010833	biological_process	telomere maintenance via telomere lengthening
G	0016233	biological_process	telomere capping
G	0032200	biological_process	telomere organization
G	0032206	biological_process	positive regulation of telomere maintenance
G	0070187	cellular_component	shelterin complex
G	0140445	cellular_component	chromosome, telomeric repeat region
J	0000723	biological_process	telomere maintenance
J	0000781	cellular_component	chromosome, telomeric region
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0010833	biological_process	telomere maintenance via telomere lengthening
J	0016233	biological_process	telomere capping
J	0032200	biological_process	telomere organization
J	0032206	biological_process	positive regulation of telomere maintenance
J	0070187	cellular_component	shelterin complex
J	0140445	cellular_component	chromosome, telomeric repeat region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 601

Chain	Residue
A	HIS49
B	CYS479
B	CYS482
B	HIS488

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN D 601

Chain	Residue
D	HIS49
E	CYS479
E	CYS482
E	HIS488

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site_id	AC3
Number of Residues	4
Details	binding site for residue ZN G 601

Chain	Residue
H	CYS479
H	CYS482
H	HIS488
G	HIS49

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site_id	AC4
Number of Residues	4
Details	binding site for residue ZN J 601

Chain	Residue
J	HIS49
K	CYS479
K	CYS482
K	HIS488

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