Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0034077 | biological_process | butanediol metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0034077 | biological_process | butanediol metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP447 |
| A | ASP474 |
| A | GLY476 |
| A | A4Y605 |
| A | HOH729 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | HOH868 |
| A | ARG69 |
| A | GLN220 |
| A | HOH810 |
| A | HOH842 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | SER129 |
| A | THR132 |
| A | HOH804 |
| A | HOH833 |
| A | HOH882 |
| A | HOH890 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 604 |
| Chain | Residue |
| A | PHE256 |
| A | GLY258 |
| A | ARG259 |
| A | GLN266 |
| A | ARG352 |
| A | ALA402 |
| A | LEU405 |
| A | TYR406 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for residue A4Y A 605 |
| Chain | Residue |
| A | PRO33 |
| A | GLY34 |
| A | ALA35 |
| A | GLU57 |
| A | ASN87 |
| A | MET394 |
| A | SER396 |
| A | PHE397 |
| A | GLN420 |
| A | MET422 |
| A | GLY446 |
| A | ASP447 |
| A | GLY448 |
| A | GLY449 |
| A | ASP474 |
| A | GLY476 |
| A | TYR477 |
| A | ASN478 |
| A | MET479 |
| A | VAL480 |
| A | TYR543 |
| A | MG601 |
| A | HOH729 |
| A | HOH807 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue PYR A 606 |
| Chain | Residue |
| A | SER97 |
| A | GLY99 |
| A | ARG159 |
| A | PRO160 |
| A | LEU216 |
| A | GLN243 |
| A | VAL286 |
| A | HOH771 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP447 |
| B | ASP474 |
| B | GLY476 |
| B | A4Y605 |
| B | HOH765 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | SER129 |
| B | THR132 |
| B | HOH834 |
| B | HOH899 |
| B | HOH950 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 603 |
| Chain | Residue |
| B | LEU44 |
| B | SER47 |
| B | ILE49 |
| B | HOH896 |
| B | HOH923 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 604 |
| Chain | Residue |
| B | GLY258 |
| B | ARG259 |
| B | GLN266 |
| B | ARG352 |
| B | TYR406 |
| B | HOH744 |
| B | HOH778 |
| site_id | AD2 |
| Number of Residues | 28 |
| Details | binding site for residue A4Y B 605 |
| Chain | Residue |
| B | TYR543 |
| B | MG601 |
| B | HOH741 |
| B | HOH742 |
| B | HOH762 |
| B | HOH765 |
| B | HOH775 |
| B | PRO33 |
| B | GLY34 |
| B | ALA35 |
| B | GLU57 |
| B | ASN87 |
| B | MET394 |
| B | GLY395 |
| B | SER396 |
| B | PHE397 |
| B | GLN420 |
| B | MET422 |
| B | GLY446 |
| B | ASP447 |
| B | GLY448 |
| B | GLY449 |
| B | ASP474 |
| B | GLY476 |
| B | TYR477 |
| B | ASN478 |
| B | MET479 |
| B | VAL480 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue PYR B 606 |
| Chain | Residue |
| A | ARG544 |
| A | ASP545 |
| B | TYR488 |
| B | GLN489 |
| B | ARG490 |
| B | HOH810 |
| B | HOH814 |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. IGawlvnPerkvVsVsGDGG |
| Chain | Residue | Details |
| A | ILE430-GLY449 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG159 | |
| A | PHE263 | |
| A | ASP304 | |
| A | ASP447 | |
| B | ARG159 | |
| B | PHE263 | |
| B | ASP304 | |
| B | ASP447 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 722 |
| Chain | Residue | Details |
| A | MET394 | electrostatic stabiliser |
| A | MET422 | steric role |
| A | ASP447 | metal ligand |
| A | ASP474 | metal ligand |
| A | GLY476 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 722 |
| Chain | Residue | Details |
| B | MET394 | electrostatic stabiliser |
| B | MET422 | steric role |
| B | ASP447 | metal ligand |
| B | ASP474 | metal ligand |
| B | GLY476 | metal ligand |
